We present a systematic investigation of the effect of solvent hydrophobicity (alkyl chain length) on the gelation kinetics and the phase states of the polypeptide gelatin in imidazolium based ionic liquid (IL) solutions. We have observed that IL concentration and hydrophobicity had dramatic influences on the thermal and viscoelastic properties of gelatin ionogels. Gelation concentration cg was...

Michael-type addition reactions are widely used to polymerize biocompatible hydrogels. The thiol-maleimide modality achieves the highest macromer coupling efficiency of the reported Michael-type pairs, but the resulting hydrogel networks are heterogeneous because polymerization is faster than the individual components can be manually mixed. The reactivity of the thiol dictates the overall react...

normal 0 false false false en-us x-none fa microsoftinternetexplorer4 background: in radiation therapy with ion beams, lateral distributions of absorbed dose in the tissue are important. heavy ion therapy, such as carbon-ion therapy, is a novel technique of high-precision external radiotherapy which has advantages over proton therapy in terms of dose locality and biological effectiveness. metho...

Phase transitions of linear multivalent proteins control the reversible formation of many intracellular membraneless bodies. Specific non-covalent crosslinks involving domains/motifs lead to system-spanning networks referred to as gels. Gelation transitions can occur with or without phase separation. In gelation driven by phase separation multivalent proteins and their ligands condense into den...

Background: Glibenclamide is a second-generation sulfonylurea extensively associated with the therapy of diabetes mellitus. A sustained release drug in gastrointestinal tract may aid maintaining therapeutic range for an extended period time. Alginate and pectin are two commonly used biopolymers field delivery favourable biodegradation biocompatibility. Materials Methods: In present study, pecti...

The aim of this work was to study the effect of xanthan gum (XG) on the gelation process of bovine sodium caseinate (NaCAS) induced by acidification with glucono-δ-lactone (GDL) and on the mixed acid gel microstructure. Before GDL addition, segregative phase separation was observed in all the NaCAS-XG mixtures evaluated. The gelation process was analyzed by using a fractional factorial experime...

The absorbance measurements in the wavelength range 700 nm to 800 nm were used to probe the agarose gel topology evolution and extract the pore size of the trapped solvent. By following the changes in absorbance and pore size, the gelation process could be clearly divided into three stages induction stage, gelation stage and pseudo-equilibrium stage. The gelation mechanism is explained as a nuc...