The inferior olive (IO) is a major component of the eyeblink conditioning neural network. The cerebellar learning hypothesis assumes that the IO supplies the cerebellum with a "teaching" unconditioned stimulus input required for the acquisition of the conditioned response (CR) and predicts that inactivating this input leads to the extinction of CRs. Previous tests of this prediction attempted t...

OBJECTIVE To investigate the effects of infant orthopedics (IO) on the language skills of children with complete unilateral cleft lip and palate (UCLP). DESIGN In a prospective randomized clinical trial (Dutchcleft), two groups of children with complete UCLP were followed up longitudinally: one group was treated with IO based on a modified Zurich approach in the first year of life (IO group);...

INTRODUCTION The intraosseous (IO) route has become a popular method to gain access to the peripheral circulation in emergency situations. Despite little supporting data, it is generally believed that IO absorption is immediate and equivalent to the intravenous (IV) route. It is important to determine if rocuronium can effectively be administered by the IO route. The aim of the study was to det...

This research paper analyzes the impact of information and network characteristics on the affective, cognitive, and behavioral attitude towards information overload (IO) on Facebook. By using an information overload model and the data of 300 active Facebook users it can be shown that the various categories of attitude are influenced by different factors. The level of determination of the behavi...

E-service development has grown to become a daily practice in most public organizations as a means for realizing digital agendas and e-government initiatives on different levels (local, regional, national and transnational governmental levels). Public e-service development is often an inter-organizational (IO) effort with multiple actors and organizations involved in the multi-faceted dimension...