نتایج جستجو برای: intravaginal

تعداد نتایج: 1564  

Journal: :Obstetrics and gynecology 2002
Luis Sanchez-Ramos Andrew M Kaunitz Isaac Delke

OBJECTIVE To systematically review published randomized controlled trials (RCTs) to compare the safety and efficacy of 25 microg versus 50 microg of intravaginal misoprostol for cervical ripening and labor induction. DATA SOURCES We supplemented a search of entries in electronic databases with references cited in original studies and review articles to identify RCTs of misoprostol for cervica...

Journal: :Menopause 2015
David J Portman Fernand Labrie David F Archer Céline Bouchard Leonello Cusan Ginette Girard Normand Ayotte William Koltun François Blouin Douglas Young Anthony Wade Céline Martel Robert Dubé

OBJECTIVE This study aims to evaluate the effects of intravaginal dehydroepiandrosterone (DHEA, prasterone) on the endometrium in postmenopausal women. METHODS Intravaginal DHEA (6.5 mg) was administered daily for 52 weeks to 422 women who had endometrial biopsy at baseline and end of study, whereas 15 women were similarly treated for 26 to 52 weeks. Participants in three other studies receiv...

Journal: :Cancer research 1983
H Okada Y Sakura H Kawaji T Yashiki H Mima

Potent luteinizing hormone-releasing hormone analogues are known to cause regression of hormone-dependent mammary tumors. We have observed that high and long-lasting serum levels of a potent luteinizing hormone-releasing hormone analogue [desglycyl10-(D-leucyl6) luteinizing hormone-releasing hormone ethylamide, leuprolide] resulted from vaginal administration which effectively caused down regul...

Journal: :Antimicrobial agents and chemotherapy 1997
B C Herold A Siston J Bremer R Kirkpatrick G Wilbanks P Fugedi C Peto M Cooper

Heparan sulfate (HS) serves as a receptor for adherence of herpes simplex viruses, Chlamydia trachomatis, Neisseria gonorrhoeae, and, indirectly, human immunodeficiency virus. Using primary human culture systems, we identified sulfated carbohydrate compounds that resemble HS and competitively inhibit infection by these pathogens. These compounds are candidates for intravaginal formulations for ...

Journal: :Genitourinary medicine 1997
D D Coelho

Management of a 42 year old female patient diagnosed with trichomoniasis is described. She failed to respond to recommended oral and high dose oral and topical metronidazole. Various options used in previously reported cases of metronidazole resistant trichomoniasis also failed to cure her condition. MIC showed the organism to be resistant to metronidazole. Cure was achieved with the use of top...

Journal: :Human reproduction update 1999
E Cicinelli D de Ziegler

The results of many recent experimental and clinical studies support the hypothesis that progesterone administered vaginally is distributed selectively to the uterus where tissue concentrations and effects exceed expectations. This phenomenon has multiple clinical implications in several fields of gynaecological endocrinology, notably in assisted reproductive treatments and new forms of hormone...

Journal: :Molecular human reproduction 2004
Helena Honkanen Eeva-Marja Rutanen Oskari Heikinheimo

The kinetics of cervical and circulating phosphoisoforms of insulin-like growth factor-binding protein-1 (IGFBP-1) in normal and pathological early pregnancy are not well known. We investigated the profiles of IGFBP-1 in serum and in cervical secretion during medical termination of early pregnancy. Sixteen women requesting termination of pregnancy, with <63 days of amenorrhoea, received 200 mg ...

Journal: :Endocrinologia japonica 1983
K P Katayama R F Mattingly

The administration of estrogens for gonadal dysgenesis is sometimes associated with the development of endometrial neoplasms. An approach which minimizes the inadvertent side effects while still providing the desired therapeutic effects may be to imitate the hormonal milieu of the normal menstruating woman. Oral administration of estradiol will not necessarily accomplish this, because of the in...

2012
James Chivian Lukban

Stress urinary incontinence is a prevalent condition in women with a significant negative effect on quality of life. Intervention includes behavioral modification, intravaginal devices, pelvic floor muscle exercises, biofeedback, functional electrical stimulation, and surgical procedures. We will review a new in-office procedure for the treatment of SUI that may serve as a viable nonsurgical op...

2013
Jimena Yapura Reuben J Mapletoft Roger A Pierson Jaswant Singh Gregg P Adams

BACKGROUND Letrozole, a non-steroidal aromatase inhibitor, prevents the body from producing its own estrogen. The objectives of the present study were to test the hypotheses that letrozole treatment, initiated prior to selection of the preovulatory dominant follicle, will induce the growth of more than one follicle to a pre-ovulatory size, and will delay ovulation. METHODS Post-pubertal beef ...

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