The density and pH of a local anesthetic are important characteristics in its use as an intrathecal drug. Preservativeand antioxidant-free formulations of chloroprocaine are available and are being investigated for short-duration spinal anesthesia. In this study, we evaluated the pH and density (to 5 significant digits in g/mL, at 37.0°C) of these new chloroprocaine formulations. In addition to...

INTRODUCTION In this study we aimed to develop a simple and practical technique for chronic sacral epidural catheterization of rabbits. METHODS We included ten rabbits weighing 2-2.5 kg in the study. After anesthesia and analgesia, we placed an epidural catheter by a 2 cm longitudinal skin incision in the tail above the sacral hiatus region. We confirmed localization by giving 1% lidocaine (l...

Studies in mice and rats have shown that antinociception produced by intrathecal (i.t.) administration of opioids can be partially inhibited by intracerebroventricular (i.c.v.) administration of naloxone. In this study we tested the hypothesis that this inhibition by i.c.v. naloxone results from antagonism of supraspinal endogenous opioid-mediated antinociception produced by the action of i.t. ...

AIM The aim of this systematic review was to evaluate the available literature on the management of pain after laparoscopic colorectal surgery. METHOD Randomized studies, published in English between January 1995 and July 2011, assessing analgesic and anaesthetic interventions in adults undergoing laparoscopic colorectal surgery, and reporting pain scores, were retrieved from the Embase and M...

Patients with spinal cord injury (SCI) may experience several types of chronic pains. Abdominal pain in patients with SCI has gained limited attention and little is yet known about its characteristics and mechanisms. It often has been regarded as visceral pain associated with constipation and distention. Neuropathic pains localized in the abdomen have rarely been reported. We experience a case ...

OBJECTIVES We wanted to determine whether any treatment had been shown to reduce pain or disability from postherpetic neuralgia (PHN), a common sequela of herpes zoster in elderly patients. STUDY DESIGN We undertook a systematic review of English-language randomized controlled trials (RCTs) of treatments of PHN with evaluation periods longer than 24 hours. DATA SOURCES We systematically sea...

Policy Aetna considers parenteral administration of dihydroergotamine (DHE) medically necessary for the treatment of intractable migraine or cluster headache. Prolonged multi-day administration of DHE is considered medically necessary when both of the following conditions are met: 1. Member has intractable cluster headache or severe migraine headache (i.e., status migrainosus, chronic daily hea...

Lamiophlomis rotata (L. rotata; Benth.) Kudo is an effective traditional herb in the clinical treatment of chronic pain syndromes in China. 8-O-acetyl shanzhiside methylester (8-OaS), a chief component in L. rotata, possesses potent immunosuppressive activities and favorable analgesic effects. This study was proposed to compare the analgesic effects of 8-OaS with those of lidocaine and ketamine...

218 Ultrasound Guided Epidural Analgesia for Labour in a Patient with an Intrathecal Baclofen Pump Abstract Type: Case Report/Case Series Manasi Badve, M.D.; Tanmay Shah, M.D.; Jeremy Rice, D.O.; Manuel Vallejo, M.D. Magee-Womens Hospital of UPMCType: Case Report/Case Series Manasi Badve, M.D.; Tanmay Shah, M.D.; Jeremy Rice, D.O.; Manuel Vallejo, M.D. Magee-Womens Hospital of UPMC Intrathecal ...