BACKGROUND In 2014, Pang et al. reported three cases with vitelliform submaculopathy as a preceding lesion of primary intraocular lymphoma (PIOL). Here, we report a case with an atypical presentation of PIOL who initially presented with vitelliform submaculopathy, vitreous haze and preripheral retinal focus. CASE PRESENTATION A 73-year-old female initially visited another hospital with a chie...

BACKGROUND Primary intraocular lymphoma (PIOL) is a subset of primary central nervous system lymphoma (PCNSL) in which lymphoma cells initially invade the retina, vitreous, or optic nerve head, with or without concomitant CNS involvement. The incidence of this previously rare condition has increased dramatically. Given its nonspecific presentation and aggressive course, PIOL provides a diagnost...

Despite recent advances in diagnosis and treatment, the prognosis of primary intraocular lymphoma (PIOL) remains poor, and the optimal treatment has yet to be defined. This review presents an overview of the current status of PIOL with a focus on recent advances in diagnosis and treatment. Recent studies show a decreasing time interval from symptom presentation to diagnosis, likely due to incre...

PURPOSE Intraocular lymphoma (IOL) frequently coexists with primary central nervous system lymphoma(PCNSL). We sought to determine the efficacy of high-dose methotrexate (MTX) alone in patients with IOL. We also sought to determine whether micromolar levels of MTX could be achieved in the aqueous and vitreous humor of the eye after i.v. administration of the drug. EXPERIMENTAL DESIGN Nine pat...

AIMS/BACKGROUND To clarify whether intraocular lens (IOL) implantation in the human eye affects the durability of polymethylmethacrylate over an average period of 10.9 years. METHODS Shearing stress and extent of damage following neodymium (Nd):YAG laser application to 18 study and 12 control optics were examined. RESULTS No significant difference was found between the study and the control...

Purpose To analyze the "in vitro" aberrometric pattern of a refractive IOL and two extended depth of focus IOLs. Methods A special optical bench with a Shack-Hartmann wavefront sensor (SH) was designed for the measurement. Three presbyopia correction IOLs were analyzed: Mini WELL (MW), TECNIS Symfony ZXR00 (SYM), and Lentis Mplus X LS-313 MF30 (MP). Three different pupil sizes were used for t...

OBJECTIVE To report two cases of concomitant choroidal melanoma and intraocular non-Hodgkin lymphoma in two patients. DESIGN Case report. PARTICIPANTS Two patients with yellow creamy infiltrates in fundo. INTERVENTION Both patients had a complete ophthalmologic evaluation and histology was obtained after enucleation of the affected eye. MAIN OUTCOME MEASURES Histology findings of the en...