Chromosomal aberrations seem to emerge as a cause of idiopathic oligo-athenoteratozoospermia. Ring Y chromosome – as one of these aberrationsthough rare, should be considered or excluded in cases of ambiguous genitalia, severe oligozoospermia, morphologic abnormalities and especially before Intra-Cytoplasmic Sperm Injection (ICSI) in suspicious cases. We report a 34 year old male patient, compl...

Background: Intracytoplasmic sperm injection (ICSI) involves mechanical transfer of a single sperm cell into ooplasm. A new application has been recently found for ICSI, the production of transgenic animals. Since the birth of ‘‘Dolly’’, the first adult somatic cloned mammal, viable offspring has been produced by nuclear transfer in many species including cattle. The present review briefly summ...

Abstract Study question In men with Raised Sperm DNA Fragmentation Index (DFI), Would advance sperm preparation techniques at Intra-Cytoplasmic Injection (ICSI) alter embryo euploidy status? Summary answer raised DFI, use of selection are safe and do not appear to ploidy status the embryos What is known already MACS (Magnetic Activated Cell Sorting), Microfluidic Sorting (MF), surgically retrie...

Background: Our Background was to evaluate the effect of ovarian endometrioma on ovarian stimulation outcomes in Intra Cytoplasmic Sperm Injection (ICSI). Materials and Methods: In this prospective cohort study, we followed 103 patients underwent ICSI procedures at royan Institute during 10 month. The study group consisted of 46 women who had endometriomawith size more than 1 cm. The control gr...

Introduction: We aimed to determine pregnancy and miscarriage rates following intracytoplasmic sperm injection (ICSI) cycles using retrieved epididymal and testicular sperm in azoospermic men and ejaculated sperm in oligospermic and normospermic men. Materials and Methods: This retrospective study was carried out on 517 couples who underwent ICSI. They included 96 couples with azoospermia and 4...

Intracytoplasmic sperm injection (ICSI) is the method of choice for fertilizing horse oocytes in vitro. Nevertheless, for reasons that are not yet clear, embryo development rates are low. The aims of this study were to examine cytoskeletal and chromatin reorganization in horse oocytes fertilized by ICSI or activated parthenogenetically. Additional oocytes were injected with a sperm labeled with...

background: in vitro fertilization (ivf) and intra cytoplasmic sperm injection (icsi) are recognized as established and increasingly successful forms of treatment for infertility, yet significant numbers of couples discontinue treatment without achieving a live birth. this study aims to identify major factors that influence the decision to discontinue ivf/icsi treatments. materials and methods:...

OBJECTIVE Globozoospermia is a rare type of teratozoospermia with incidence of 0.1% among infertile individuals. Phospholipase C zeta (PLCζ) and postacrosomal sheath WW domain binding protein (PAWP) are the main candidates in sperm taking responsibility for oocyte activation during fertilization. Therefore, we aimed to evaluate the expression of these two genes at RNA and protein levels in glob...

OBJECTIVE To investigate the effectiveness of intracytoplasmic sperm injection (ICSI) using testicular sperm as a strategy to overcome infertility in men with high sperm DNA fragmentation (SDF). DESIGN Prospective, observational, cohort study. SETTING Private IVF centers. PATIENT(S) A total of 147 couples undergoing IVF-ICSI and day 3 fresh ETs whose male partner has oligozoospermia and h...