BACKGROUND Rosacea is a chronic facial skin disease associated with excessive inflammatory response to various triggers. Although some studies have supported the increased risk of cardiovascular diseases in rosacea, it has not been completely accepted. OBJECTIVE We aimed to investigate epicardial fat thickness and carotid intima-media thickness as cardiovascular risk predictors in rosacea pat...

The inhibitory effect of manidipine, a long acting calcium channel blocker, on vascular smooth muscle cell proliferation was investigated in spontaneously diabetic GK rats with balloon catheter-induced denudation of the carotid artery. Treatment with manidipine at doses of 4.6 and 15.1 mg/kg/day inhibited thickening of the neo-intima in the balloon catheter-injured artery without any effect on ...

One of the locations of renal artery atherosclerosis is at the orifice of the renal artery, therefore thestructure of this orifice was assessed in 6 normal, adult male dogs by light microscopy (LM) andtransmission electron microscopy (TEM). For the LM study, processed tissues were embedded in paraffinand sectioned serially into 6-μm thickness. Sections were stained with orcein. For the TEM stud...

In a preliminary study, foam cells from atherosclerotic lesions have been isolated by incubation of the intima with collagenase and elastase. The composition and metabolism of homogeneous preparations of foam cells obtained in this way have been compared with other parts of the atherosclerotic intima. About 1% of the cholesterol and phospholipid of the intima was present in the cells obtained. ...

BACKGROUND The intima-media thickness of carotid arteries measured with B-mode ultrasound is a measurable index of the presence of atherosclerosis. Physical inactivity is known to be a risk factor for rapid onset and progression of atherosclerosis. Objective of the study was to evaluate the influence of leisure time physical activity on carotid intima media thickness in middle aged Pakistani po...

The synthesis of lipid by rabbit atherosclerotic intima incubated in vitro has been investigated and compared with that of foam cells isolated from intima] lesions. In the atherosclerotic arterial intima, C-labeled acetate is readily incorporated into the lipid fraction, most of the label being found in the phospholipid and cholesterol ester fatty acid fractions. Minimal incorporation into trig...

High-resolution B-mode ultrasonography of the carotid arteries is used to investigate the signs of early atherosclerotic vessel wall disease. To assess whether carotid artery findings reflect atherosclerosis elsewhere, we studied the association between common carotid intima-media thickness and lower extremity arterial atherosclerosis among the first 1000 participants of the Rotterdam Study. Th...

Purpose: Subclinical atherosclerosis defined as endothelial dysfunction, coronary calcification, and increased carotid intima media thickness is related to cardiovascular events independent from blood pressure. There are data showing possible relation between low vitamin D levels and subclinical atherosclerosis. In this study we aimed to find out the relation between vitamin D level and intima ...

OBJECTIVES The purpose of this study was to examine the relationship between apolipoprotein (a) isoforms and early atherosclerosis, assessed by carotid artery intima-media thickness in a sample of adults of the general population of Burgos, a city in the north of Spain. DESIGN AND METHODS Lipids, lipoprotein (a), number of carotid atherosclerotic plaques, if any, and the intima-media thicknes...