The purpose of the study was to analyze modern literature on problems dysbiosis in patients with COVID-19, main mechanisms systemic interaction between intestine and lungs, as well changes microbiota that occur under influence coronavirus infection. Materials methods. A comprehensive selection research methods used for work: systematization material, method generalization, analysis synthesis. S...

Background. ß-lactam antibiotics that are excreted into the intestine can damage the microflora, which can lead to serious infections such as Clostridium difficile (C. diff ). SYN-004 is a potent ß-lactamase formulated for oral use with intravenous (IV) antibiotics to degrade antibiotics in the intestine. Methods. SYN-004, formerly called P3A, was developed and evaluated by Ipsat Therapies, Hel...

Chronic oxidative stress impairs regular defecation. Sulforaphane (SFN) enhances anti-oxidant systems, ameliorating oxidative injury. SFN inhibits overgrowth of anaerobic microflora and protects small intestine from oxidative injury. We assessed whether daily intake of SFN-rich broccoli sprouts (BS) improves defecation in humans. Forty-eight subjects, with a constipation scoring system (CSS) >2...

The effect of supplementing piglet diets with acidifiers containing the short-chain fatty acids - SCFA (propionic C3 and formic) together with medium-chain fatty acids -- MCFA (caprylic C8 and capric C10) on performance, nutrient apparent digestibility, intestinal microflora and small intestine structure was investigated. The study was performed on 326 piglets allocated to 5 experimental groups...

we described a case of lymphoid follicular hyperplasia that arose from the ileum of a 52-year-old woman. her colonoscopy revealed a large mass in the cecum associated with multiple polypoid lesions in the ileum. histologic examination demonstrated severe lymphocytic infiltration and lymphoid follicles with regular germinal centers, without evidence of malignancy. a right hemicolectomy was perfo...

Ulcerative colitis is a severe, relapsing and remitting disease of the human large intestine characterised by inflammation of the mucosa and submucosa. The main site of disease is the sigmoid/rectal region of the large bowel but the aetiology remains unknown. There is considerable evidence to indicate that the components of the resident colonic microflora can play an important role in initiatio...

Baicalin, a main constituent of the rhizome of Scutellaria baicalensis, is metabolized to baicalein and oroxylin A in the intestine before its absorption. To understand the role of intestinal microflora in the pharmacological activities of baicalin, we investigated its anti-inflammatory effect in mice treated with and without antibiotics. Orally administered baicalin showed the anti-inflammator...

Lactic acid bacteria (LAB) are present in the intestine of most animals. The beneficial role played by these microorganisms in the humans and other animals, including the effect on the immune system, has been extensively reported. They are present in many foods and are frequently used as probiotics to improve some biological functions in the host. The activation of the systemic and secretory im...

During fetal development, lymphoid tissue inducer cells (LTis) seed the developing lymph node and Peyer's patch anlagen and initiate the formation of both types of lymphoid organs. In the adult, a similar population of cells, termed lymphoid tissue inducer-like cells (LTi-like cells), supports the formation of organized gut-associated lymphoid tissue (GALT) in the intestine, including both isol...

industrially important microorganisms used for the production of various fermented foods. Recently, probiotic lactic acid bacteria defined as “living microorganisms that benefit the health of the host by conditioning the intestinal environment” have attracted the attention of many scientists, and began to be applied in the dairy industry. For example, the intake of fermented milk containing pro...