نتایج جستجو برای: intestinal polyposis
تعداد نتایج: 141322 فیلتر نتایج به سال:
Introduction & Objective : Chronic rhinosinusitis (C.R.S.) is one of the most common diseases in the world. Polyposis is a complication of C.R.S., due to allergy or inflammation. The purpose of this study was detection of the incidence of polyposis in patients with C.R.S. Materials & Methods : This study was carried out on 192 patients with C.R.S. who underwent functional endoscopic sinus su...
Peutz-Jegher syndrome (PJS) is a rare, autosomal-dominant disorder characterized by hamartomatous polyps in any part of the alimentary tract, and almost always associated with intestinal polyposis and mucocutaneous pigmentation (1). Rarely, solitary PJP arise inpatients without other features of PJS. A review of the English literature revealed only 6 published cases since 1989. Here, we would l...
A 13-year-old girl presented with features of intestinal obstruction. At surgery, the terminal 25 cm of ileum, which was resected along with the right colon, showed plexiform neurofibromatosis of the serosa and mesentery, hyperplastic submucosal and myenteric nerve plexuses and proliferation of neural tissue in the lamina propria, which manifested as diffuse polyposis of the ileal mucosa. The p...
127 Received August 25, 2014; revised and accepted January 28, 2015. Published online February 20, 2015; doi: 10.1620/tjem.235.127. Correspondence: Takeshi Sato, M.D., Department of Gastroenterology, Yamagata University Faculty of Medicine, 2-2-2 Iida-Nishi, Yamagata, Yamagata 990-9585, Japan. e-mail: [email protected] Treatment with Anti-Interleukin-6 Receptor Antibody Ameliorat...
Two cyclooxygenase isozymes catalyze conversion of arachidonic acid to prostaglandin H2: constitutive COX-1 and inducible COX-2. To assess the role of COX-2 in colorectal tumorigenisis, we determined the effects of COX-2 gene (Ptgs2) knockouts and a novel COX-2 inhibitor on Apc delta716 knockout mice, a model of human familial adenomatous polyposis. A Ptgs2 null mutation reduced the number and ...
Mucosal biopsy specimens from the ileal reservoirs of 92 patients who had undergone restorative proctocolectomy (12 with familial adenomatous polyposis, 78 with ulcerative colitis, and two with functional bowel disease) were studied. Chronic inflammation was found in almost all, as was villous atrophy of varying severity. Other changes included pyloric metaplasia and mucosal prolapse. Acute inf...
The field of radiological small-bowel imaging is changing rapidly, as is small-bowel enteroscopy. New techniques allow the depiction of intraluminal, mural, and extraintestinal features of various small-bowel disorders, such as Crohn's disease, small-bowel polyposis syndromes, small-intestinal malignancies, and coeliac disease. For patients in need of repeated small-bowel imaging, modalities th...
Epigenetic modulators, particularly histone deacetylases (HDACs), are valid targets for cancer prevention and therapy. Recent studies report that HDAC2 overexpression is associated with colon tumor progression and is a potential target for colon cancer prevention. This study tested chemopreventive and dose-response effects of Ohio State University HDAC42 (OSU-HDAC42), a selective HDAC2 inhibito...
Peutz-Jeghers syndrome is a rare condition characterized by mucocutaneous pigmentation, polyposis and an increased cancer risk at a number of gastrointestinal and extra intestinal organs. We present a patient with a history of gastrointestinal bleeding with no mucocutaneous pigmentation. Upper and lower gastrointestinal endoscopy revealed multiple polyps located in the deuodenum and colon. Hist...
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