Two possible reactive sites (the oxo site and the Ru site) for water on a high-valent ruthenium(V) oxo complex were examined. Our results suggest that the reaction on the ruthenium (via a seven coordinate intermediate) has both a lower barrier and a product with a lower free energy than the product of addition at the oxo.

An unreported product outcome from an intended Sonogashira coupling is presented. The generality of this finding has been demonstrated by screening of a range of pre-catalysts. Mechanistic studies are consistent with the tetra-aryl benzene product forming by interception of the aryl halide oxidative addition intermediate by repeated acetylene insertion.

The traditional technique to generate a global state graph representation for a concurrent system is to calculate the product of state graph representations of the local processes We develop new techniques and prove their correctness to help condensing intermediate state graphs in the iterative product calculation Experiments with Fischer s timed mutual exclusion protocol have been carried out ...

A route is described for the enantioselective synthesis of (R)-(-)-complanine, a marine natural product isolated from Eurythoe complanata, and known to be a causative agent in inflammation. An organocatalytic, asymmetric oxyamination of a homoconjugated all-Z-dienal intermediate provides versatile and efficient access to the natural product.

A highly functionalized intermediate in the synthesis of Taxol has been synthesized, which features the tricyclic core and the required oxygen substituents at C1, C2, C7, C10, and C13. The key step, a ring-closing dienyne metathesis (RCDEYM) reaction, has been thoroughly optimized to favor the tricyclic product over the undesired bicyclic product resulting from diene metathesis.

In Vietnam, especially central Vietnam, patients with fascioliasis are increasingly being reported. Since the fascioliasis is zoonotic, survey on the cattle fascioliasis should be informative for the control of human fascioliasis. In this study, the prevalence of cattle fascioliasis as well as the density of the intermediate host snails, Lymnaea swinhoei and L. viridis, were studied in Thua Thi...

The possible occurrence of phosphorylation of proadrenocorticotropin(ACTH)/endorphin-derived peptides in the rat was examined by incubating dissociated anterior and intermediate pituitary cells with a %amino acid plus 32Pi. In both lobes of the pituitary newly synthesized pro-ACTH/endorphin was labeled with 32P. In the intermediate pituitary, corticotropin-like intermediate lobe peptide (CLIP) ...

The intermediate lobe of the pituitary contains the alpha-amidated peptide alpha-melanotropin and high levels of a copper and ascorbate-dependent peptidylglycine alpha-amidating monooxygenase (PAM) capable of converting peptides terminating in -X-Gly into amidated products (-X-NH2). As reported previously, the ability of cultured intermediate pituitary cells to produce alpha-amidated alpha-mela...

In this paper, we introduce and study  a mapping from the collection of all  intermediate rings of $C(X)$ to the collection of all  realcompactifications of $X$ contained in $beta X$. By establishing the relations between this mapping and its converse,  we give a different approach to the main statements of De et. al. Using these, we provide different answers to the   four basic questions...