Submit Manuscript | http://medcraveonline.com Abbrevations: CNS: Central Nervous System; NREM: NonRapid Eye Movement; REM: Rapid Eye Movement; vEEG: Video Electroencephalography; PSG: Polysomnography; IED: Interictal Epileptiform Discharges; SSMA: Supplementary Sensorimotor Area; JME: Juvenile Myoclonic Epilepsy; TLE: Temporal Lobe Epilepsies; NTLE: Nocturnal Temporal Lobe Epilepsy; SW: SpikeWa...

Various presenters, including the undersigned, described the fact that autism itself is associated with increased risk of epilepsy. In addition, interictal epileptiform discharges (IEDs) are quite frequent (6–61%), and epilepsy is said to occur in approximately 5–30 percent of individuals on the spectrum. It is felt that the yield of epileptiform discharges increases during prolonged sleep. How...

SLEEP AND EPILEPSY ARE INTIMATELY RELATED AND INFLUENCE EACH OTHER.1 FOR EXAMPLE, FLUCTUATIONS OF ALERTNESS INDUCE QUALITATIVE AND quantitative changes of EEG epileptiform abnormalities. Conversely, epileptic activity may alter sleep architecture.2 In particular, sleep deprivation (SD) is capable of influencing ictal/interictal epileptic activities.3 SD may induce seizures in patients with epil...

PURPOSE Single-pulse electrical stimulation (SPES) during intracranial recordings is part of the epilepsy presurgical evaluation protocol at King's College Hospital (London). Epileptiform responses correlated to the stimulus (delayed responses - DRs) tend to occur in areas of seizure onset, thereby allowing interictal identification of epileptogenic cortex in patients suffering refractory epile...

Interictal and ictal discharges represent two different forms of abnormal brain activity associated with epilepsy. Ictal discharges closely parallel seizure activity, but depending on the form of epilepsy, interictal discharges may or may not be correlated with the frequency, severity, and location of seizures. Recent voltage-imaging studies in slices of piriform cortex indicated that intericta...

Submit Manuscript | http://medcraveonline.com Abbrevations: CNS: Central Nervous System; NREM: NonRapid Eye Movement; REM: Rapid Eye Movement; vEEG: Video Electroencephalography; PSG: Polysomnography; IED: Interictal Epileptiform Discharges; SSMA: Supplementary Sensorimotor Area; JME: Juvenile Myoclonic Epilepsy; TLE: Temporal Lobe Epilepsies; NTLE: Nocturnal Temporal Lobe Epilepsy; SW: SpikeWa...

PURPOSE To describe clinical and electrographic characteristics of seizures LGI1-antibody encephalitis, and their correlations with two-year outcomes. METHODS Video-electroencephalography recordings were performed on a cohort of 16 consecutive patients with LGI1-antibodies from two UK neuroscience-centers over five-years. RESULTS From 14 of 16 patients (13 males; age-range 53-92years), 86 f...

Medication withdrawal (MW) is an important method of provoking seizures and activating epileptiform EEG activity during the diagnostic work-up of patients evaluated for epilepsy surgery. Previously it was suggested that MW might influence the seizure-type and activate cortical areas otherwise not producing epileptiform discharges, leading to a false localization of the irritative zone. In order...

PURPOSE To demonstrate the significance of simultaneous electroencephalography (EEG) recording during 2-deoxy-2-[(18)F] fluoro-D-glucose (FDG)-positron emission tomography (PET) in childhood partial epilepsy. MATERIALS AND METHODS We included 46 children with partial epilepsy who underwent simultaneous EEG during PET. We compared the epileptogenic area of several EEG features including epilep...

INTRODUCTION Electroencephalography (EEG) is a non-invasive investigation method playing an important role in differential diagnostics of seizures. In this article authors point out to its importance, but also limitations. MATERIAL AND METHODS Native interictal EEG findings were evaluated in inpatients after solitary unprovoked epileptic seizures (n=84), patients with sporadic epileptic seizu...