نتایج جستجو برای: interchromosomal effect
تعداد نتایج: 1642066 فیلتر نتایج به سال:
HE first evidence of a crossover suppressor was found in 1913 by T STURTEVANT. In 1921 STURTEVANT found the first definite evidence of an inversion when he showed that several third chromosome genes in Drosophila melanogaster were arranged in an inverted order with respect to similar genes in the third chromosome of D. simulans. At this time STURTEVANT predicted that a heterozygous inversion wo...
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant myopathy, clinically characterized by asymmetric weakness of muscles in the face, shoulder girdle and upper arm. Deletion of an integral number of 3.3 kb repeated units within a highly polymorphic EcoRI fragment at chromosome 4q35, generating a relatively short EcoRI fragment (< 35 kb), has been shown to cause FSHD1. Probe p...
We have examined spontaneous, interchromosomal mitotic recombination events between his4 alleles in both Rad+ and rad52 strains of Saccharomyces cerevisiae. In Rad+ strains, 74% of the His+ prototrophs resulted from gene conversion events without exchange of flanking markers. In diploids homozygous for the rad52-1 mutation, the frequency of His+ prototroph formation was less than 5% of the wild...
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