The highly polymorphic swine major histocompatibility complex (MHC), termed swine leukocyte antigen (SLA), is associated with different levels of immunologic responses to infectious diseases, vaccines, and transplantation. Pig breeds with known SLA haplotypes are important genetic resources for biomedical research. Canadian Yorkshire and Landrace pigs represent the current specific pathogen-fre...

Monocyte subsets have been shown to differ in the pattern of chemokine receptor expression and their migratory properties, both in human and mouse. Previously we have characterized in the swine several monocyte subpopulations, based on the expression of CD163, Tük4 and SLA-II, which share features with the populations described in human and mouse. Here, we have analysed the expression of differ...

Cloud computing markets face challenges, such as a large variety of different resource types in the market. A large variety of resource types results in a low number of matches of ask and bids. Consequently, the market has a low liquidity, which is economically inefficient and can lead to market failure. To counteract this problem, SLA templates (i.e., templates for electronic contracts) have b...

This case study reports a rare variation of the superior laryngeal artery (SLA), which is the principal arterial supply of the larynx. The knowledge of the arterial variations is essential for the surgeons to prevent blood loss and postoperative complications. During routine dissection of an adult male cadaver, a rare arterial variation in the SLA was seen. In this case, the SLA passed through ...

SLA monitoring is difficult to automate as it would need precise and unambiguous specification and a customizable engine that collects the right measurement, models the data and evaluates the SLA at certain times or when certain events happen. Also most of the SLA neglect client side measurement or restrict SLAs to measurements based only on server side. In a cross-enterprise scenario like web ...

Service-level agreements (SLA) definition and monitoring are open issues within the IT Service Management (ITSM) domain. Our main goals are to propose a model-based approach to IT services SLA specification and compliance verification. The specification will be accomplished by proposing a SLA language a domain specific language for defining quality attributes as non functional requirements (NFR...

The mechanisms by which CTLA4Ig exerts its powerful immunomodulatory effects are not clear. We show here that CTLA4Ig can induce linked regulation of allogeneic porcine T cell responses in vitro. Naive miniature swine SLA(dd) T cells were rendered hyporesponsive to specific allogeneic Ag after coculturing with MHC-mismatched SLA(cc) stimulators in the presence of CTLA4Ig. These Ag-specific hypo...

Cloud computing has become a popular paradigm for implementing scalable computing infrastructures provided on-demand on a case-by-case basis. Selfmanageable Cloud infrastructures are required in order to comply with users’ requirements defined by Service Level Agreements (SLAs) and to minimize user interactions with the computing environment. Thus, adequate SLA monitoring strategies and timely ...