Building on concepts from a resource-based view of a firm and real option theory we propose a model that describes the links between a firm options development and the expected profitability. Empirical results of structural equation models on the video-game industry indicate that (i) the balance between industry innovativeness and firm inno-vativeness affects the perception of potential option,...

The global extensively drug-resistant tuberculosis (TB) response plan calls for implementation of rapid tests to screen patients at risk of drug-resistant TB. Currently, two line probe assays exist, the INNO-LiPA(R)Rif.TB assay (Innogenetics, Ghent, Belgium) and the GenoType MTBDR assay (Hain LifeScience GmbH, Nehren, Germany). While LiPA studies have been reviewed, the accuracy of GenoType ass...

This study establishes a theoretical framework and provides empirical evidence related to the motivations and benefits sought by store-loyal customers. From a theoretical perspective, the proposed framework distinguishes utilitarian benefits, such as monetary and time savings, from hedonic benefits, such as shopping enjoyment, inno-vativeness and impulsiveness. From a methodological perspective...

In recent years, multinational corporations have increasingly adopted a global approach to research and development initiatives, offshoring these activities towards different parts of the world and establishing global R&D networks. By doing so they aim to acquire highly skilled science and engineering talent (Lewin et al. 2009), increase proximity to their customer bases (Trefler, 2005), and re...

OBJECTIVE To study the performance of three rapid low cost methods for the detection of rifampicin resistance. METHODS A panel of 20 coded Mycobacterium tuberculosis strains was tested blindly by the low cost methods: nitrate reductase, MTT and resazurin assays, and compared with the results obtained with the gold standard methods: the proportion method on Löwenstein-Jensen medium and the BAC...

A PCR-based reverse hybridization system (research prototype kit INNO-LiPA for H. pylori resistance) was developed and evaluated for simultaneous detection of 23S ribosomal DNA point mutations, associated with macrolide resistance in Helicobacter pylori. Fifty-seven H. pylori strains (51 natural, 6 laboratory-derived artificial, 52 resistant, and 5 susceptible strains) were tested by PCR-LiPA (...

Fibrotic disorders involve replacement of normal parenchyma with myofibroblasts, which deposit connective tissue, leading to obliteration of the function of the underlying organ. The treatment options are inadequate and reflect the fact that signaling targets in myofibroblasts are unknown. Here we identify the hyperactive Lyn signaling in myofibroblasts of patients with chronic pancreatitis-ind...

Abstract. In the course of substantiating prospects for state regulation innovative development agro-industrial complex in context digital transformation, study synthesized a set provisions that specify author's views on these issues, revealing features combining and tools processes aimed at activating innovations industry.The main objective is to develop strategy support inno-vative technologi...