نتایج جستجو برای: informative markers

تعداد نتایج: 246328  

Journal: :Journal of medical genetics 1983
M A Spence J L Bader D M Parry L L Field S J Funderburk A E Rubenstein P A Gilman R S Sparkes

Linkage analysis of 28 genetic markers was undertaken in 108 subjects from 11 families with well-documented, classic, peripheral neurofibromatosis. Fifty-four persons were affected in one four-generation family, seven three-generation families, and three two-generation families. Lod scores were calculated using the standard LIPED programme for 49 combinations of theta male and theta female from...

Hatami Maleki, Hamid , Kheiri, Azizolah , Soleimani, Ali , Zeinolabedini, Mehrshad , Zirak, Roya ,

Genetic diversity among Russian olive genotypes in three different regions of East-Azerbaijan province (includes Tabriz, Maragheh and Malekan) were assessed using morphological and molecular (AFLP) markers. Results of the quantitative and qualitative traits statistics showed a significant genetic variation among studied germplasm and categorized them in five distinguished groups. The most numbe...

Journal: :Pharmacogenetics and genomics 2007
Guilherme Suarez-Kurtz Daniela D Vargens Claudio J Struchiner Luciana Bastos-Rodrigues Sergio D J Pena

BACKGROUND AND OBJECTIVE Skin color and self-reported ethnicity have systematically been used in the pharmacogenetic/-genomic literature as phenotypic proxies for geographical ancestry. Population admixture, however, challenges the appropriateness of this approach. We compared the effectiveness of color-based and marker-based biogeographical ancestry classifications in typing polymorphisms in G...

Journal: :American journal of human genetics 2007
Alkes L Price Nick Patterson Fuli Yu David R Cox Alicja Waliszewska Gavin J McDonald Arti Tandon Christine Schirmer Julie Neubauer Gabriel Bedoya Constanza Duque Alberto Villegas Maria Catira Bortolini Francisco M Salzano Carla Gallo Guido Mazzotti Marcela Tello-Ruiz Laura Riba Carlos A Aguilar-Salinas Samuel Canizales-Quinteros Marta Menjivar William Klitz Brian Henderson Christopher A Haiman Cheryl Winkler Teresa Tusie-Luna Andres Ruiz-Linares David Reich

Admixture mapping is an economical and powerful approach for localizing disease genes in populations of recently mixed ancestry and has proven successful in African Americans. The method holds equal promise for Latinos, who typically inherit a mix of European, Native American, and African ancestry. However, admixture mapping in Latinos has not been practical because of the lack of a map of ance...

Journal: :Proceedings. Biological sciences 2008
Rebecca Clark Sarah M Brown Steve C Collins Chris D Jiggins David G Heckel Alfried P Vogler

The swallowtail butterfly, Papilio dardanus, is an iconic example of a polymorphic Batesian mimic. The expression of various female-limited colour forms is thought to be controlled by a single autosomal locus, termed H, whose function in determining the wing pattern remains elusive. As a step towards the physical mapping of H, we established a set of 272 polymorphic amplified fragment length po...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علامه طباطبایی - دانشکده ادبیات و زبانهای خارجی 1389

abstract tasks nowadays are at the center of attention in sla research. task types is one of the critical issues in this regard, their effectiveness and suitability to any particular context, their characteristics and the result they yield are among some of these issues. on the other hand, discourse markers (dms) have been very much investigated and their effectiveness in conveying the meaning...

Journal: :Hypertension 1999
F Soubrier

Because of the complex and multiorgan origin of hypertension, the genetic approach is the preferred strategy for discovering genes predisposing to the disease, a strategy that was successful mostly for monogenic forms of the disease. Both linkage studies in families with informative markers and case-control studies with biallelic markers or putative functional variants on candidate genes were w...

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