Neuro-inflammation is a growing concern that is the result of nervous tissue inflammation. Some common causes that induce this problem are toxic metabolites, aging, autoimmunity, air pollution, et cetera. Glial cells and a group of proteins which are called cytokines are associated in neuro-inflammation. Some nervous diseases such as: Parkinson's disease, Alzheimer's disease and Multiple Sclero...

introduction: open-apex teeth with irreversible pulpitis require complex and difficult treatment. providing the right environment for apexogenesis and pulp protection is vital for their long term prognosis. the young pulp of open apex tooth, however, is better equipped against irritation and assault. the aim of this study was to evaluate pulp inflammation in open apex canine teeth of cats. mate...

depression is a mental disorder that results from changes in the central nervous system (cns) that may result from immunological abnormalities. according to the world health organization, major depression will become the leading cause of disability worldwide. accumulating evidence has indicated the existence of reciprocal communication pathways between nervous, endocrine and immune systems. the...

macrophages accumulate in poorly vascularised and hypoxic sites including solid tumours, wounds and sites of infection and inflammation where they can be exposed to low levels of oxygen for long periods. up to date, different studies have shown that a number of transcription factors are activated by hypoxia which in turn activate a broad array of mitogenic, pro-invasive, pro-angiogenic, and pro...

introduction: helicobacter pylori (h. pylori) is a gastric pathogen of primates and causes active chronic gastritis as well as peptic ulcers. a wide range of studies is in effect to prevent or cure helicobacter infection and thus its associated disorders. in order to test various drug regimens as well as potential vaccines against h. pylori infection, a suitable animal model is required which s...

background: we studied the effects of high protein (hp) and balanced diets (bds) on lipid profiles, and high‑sensitive c‑reactive protein (hs‑crp) levels in obese and overweight women. methods: in a parallel designed randomized controlled clinical trial, 60 healthy women with body mass index ≥25 kg/m2, aged 20–46 years, enrolled in an 8‑week investigation at aerobic clubs. they were categorized...

marginal zone lymphoma (mzl) accounts for between 5% and 17% of all non-hodgkin lymphomas (nhl). w e reported a rare case of marginal zone lymphoma presenting with bilateral ear erythema and swelling. the case was a 79-year-old man who suffered from progressive bilateral ear erythema and swelling since 2 years ago. physical examination was remarkable for erythmatous, edematous and non-tender au...

honey bee sting is used in some societies as a treatment of inflammation in joint diseases such as arthritis. to investigate the effect of honey bee venom in reducing inflammation, we selected 30 male wister rats which were divided in to 6 groups. except group 1, all remaining groups received 0.5 ml of complete freund’s adjuvant to induce arthritis. after 9 days, all animals that received adjuv...

conclusions no significant difference in reducing post bypass inflammation between preoperative steroid treatment and combined preoperative and intraoperative steroid administration reported and they had the same effects. results in both groups, no significant difference with variation of expression for il-6 (inflammatory factor) and il-10 (anti-inflammatory factor) in different times after byp...