The prevalence of depression and anxiety in the Chinese male population with infertility is still uncertain. The prevalence of depression, anxiety, and a combination of both psychological symptoms was 20.8%, 7.8%, and 15.4%, respectively in 771 infertile Chinese men in the current study by the Mental Health Inventory-5 and the State-Trait Anxiety Inventory-Short Form questionnaires. Differences...

Purpose A hysteroscopic metroplasty was performed for women with recurrent pregnancy loss owing to a uterine septum, following which some women became infertile. The aim of this study was to elucidate the risk factors of secondary infertility 1 year after hysteroscopic metroplasty for a uterine septum. Methods A retrospective, single-center, cohort study included women with a history of at le...

background: the piwi-interacting rna (pirna) pathway has an essential role in transposon silencing, meiosis progression, spermatogenesis, and germline maintenance. hiwi genes are critical for pirna biogenesis and function. therefore, polymorphisms in hiwi genes contribute to spermatogenesis defects and can be considered as risk factors for male infertility. the aim of the present study was to i...

context correct timing of diagnostic laparoscopy for unexplained infertility management remains as a debate for clinicians. a cost-effective strategy of diagnostic laparoscopy utilization for unexplained infertile patients is much needed. evidence acquisition detailed evaluation of the articles extracted from a “pubmed” and “cochrane database” search using “unexplained infertility and diagnosti...

INTRODUCTION Endometriosis is defined as overgrowth of endometrial tissue outside the uterine cavity. Endometriosis may be asymptomatic or associated with dysmenorrheal symptoms, dyspareunia, pelvic pain, abnormal uterine bleeding and infertility. The aim of this study was to explore the risk factors related to endometriosis among infertile Iranian women. MATERIAL AND METHODS In this case con...

Background Preterm birth significantly affects the neonates’ survival. It also increases the risk of neonatal complications, prolongs the hospitalization period, and imposes high costs on the public health system. This study is aimed to assess the risk factors of the preterm birth. Materials and Methods This case-control stud...

s:1858:"Background: Infertility is defined as inability in pregnancy after one year of regular intercourse without using contraceptive methods. Approximately15-10% of couples in childbearing appears infertile. It is the cause of infertility in men and women and infertility treatment depends on type of failure and is one of the methods of treating infertility in vitro fertilization. This researc...

evidence acquisition literature searching for studies on female infertility and micronutrient intakes, published between january 1984 and november 2014, was performed using the pubmed and embase databases. the bibliographies of included studies were also searched for additional references. results about 100 articles were identified and after the elimination of irrelevant studies, 28 related stu...

We evaluate the association between genetic polymorphisms of XRCC5 VNTR, XRCC6 -61C>G, and XRCC7 6721G>T with male infertility susceptibility. A total of 392 men including 178 infertile males (102 idiopathic azoospermia and 76 severe oligozoospermia) and 214 healthy controls were recruited. XRCC6 -61C>G and XRCC7 6721G>T genotyping was performed by PCR-RFLP whereas XRCC5 VNTR was performed by P...

The TP53, a transcriptional regulator and tumor suppressor, is functionally important in spermatogenesis. MDM2 is a key regulator of the p53 pathway and modulates p53 activity. Both proteins have been functionally linked to germ cell apoptosis, which may affect human infertility, but very little is known on how common polymorphisms in these genes may influence germ cell apoptosis and the risk o...