نتایج جستجو برای: inferiority feelings
تعداد نتایج: 22583 فیلتر نتایج به سال:
PURPOSE The current methods used to evaluate the efficacy of drug products are inadequate. We propose a non-inferiority approach to prove the safety of drugs. MATERIALS AND METHODS Traditional hypotheses for the evaluation of the safety of drugs are based on proof of hazard, which have proven to be inadequate. Therefore, based on the concept of proof of safety, the non-inferiority hypothesis ...
Meertens’ subtle and blatant scales (1992, 1995). Its objective is to determine if the structure originally proposed by these authors is supported by data collected in the Chilean social environment and if this instrument, that theoretically detects modern prejudice manifestations, is useful to appropriately distinguish between old and new forms of ethnic prejudice. The premise underlying new f...
BACKGROUND There is concern that non-inferiority trials might be deliberately designed to conceal that a new treatment is less effective than a standard treatment. In order to test this hypothesis we performed a meta-analysis of non-inferiority trials to assess the average effect of experimental treatments compared with standard treatments. METHODS One hundred and seventy non-inferiority trea...
PURPOSE Epidermal growth factor receptor (EGFR) inhibitors are approved for treating metastatic colorectal cancer (CRC); KRAS mutation testing is recommended prior to treatment. We conducted a non-inferiority analysis to examine whether KRAS testing has impacted survival in CRC patients. PATIENTS AND METHODS We included 1186 metastatic CRC cases from seven health plans. A cutpoint of July, 20...
Child abuse has become prevalent in the society and reached an alarming state. An experience of creates a domino effect on child’s learning socialization school, consequently impacts their holistic development. Anchoring B.F. Skinner’s Operant Conditioning Theory, this study investigates undesirable school behaviour abused children formulates intervention program for modification. This case doc...
Non-inferiority (NI) trials attempt to demonstrate that the loss in efficacy by a new treatment compared to a standard treatment is limited to a certain pre-specified margin, usually compensated by some form of benefit in the form of safety, ease in administration, tolerability, costs, etc. The lack of mention of the benefit of the new treatment and its importance have been pointed out recently...
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