BACKGROUND Chronic rhinosinusitis with nasal polyps (CRSwNP) is a multifactorial disease; the underlying mechanisms of cell signalling are not fully understood. STAT3 (signal transducer and activator of transcription 3) is a phosphokinase and a key signalling molecule implicated in cell cycle regulation. We studied the distribution and expression of STAT3 to examine the role of STAT3 in the pat...

Nasal obstruction resulting from inferior turbinate hypertrophy (ITH) was treated with Nd YAG laser inferior turbinectomy (Laser IT). The effectiveness of the procedure was assessed and compared with both Functional Endoscopic turbinoplasty (Turbinoplasty) and conventional partial turbinectomy (Conventional IT). Materials and methods: A retrospective analytic study was carried out for 53 patien...

Two auxiliary methods of diagnosing nasopharyngeal airway obstruction were compared. Cephalometric radiography and nasopharyngeal videoendoscopy were evaluated for efficacy in terms of reproducibility and validity. Thirty orthodontic patients (7 to 12 years of age) seeking otorhinolaryngologic treatment for mouth breathing, or mouth and nose breathing, had nasopharyngeal endoscopy and radiograp...

BACKGROUND AND OBJECTIVES Nasal septal deviation (NSD) is often associated with overgrowth of the unilateral inferior turbinate. In vivo and in vitro studies indicate that human mesenchymal stem cells (MSCs) are able to differentiate into multiple cell types, including osteoblasts. We tested the hypothesis that turbinate size affects human turbinate-derived MSC (hTMSCs) quantity, proliferation,...

We submit the case of an 11-year-old boy under treatment for acute lymphoblastic leukaemia, who presented with fever, headache and nasal congestion. Due to the persistence of the symptoms, he received a computed tomography (CT) scan of the nasal sinus, revealing the existence of pansinusitis. Incidentally, a space-occupying bone lesion, hyperdense in the inferior turbinate, was identified (Figs...

OBJECTIVES To compare the efficacy of power-microdebrider-assisted inferior turbinoplasty (PAT) with submucosal resection (SMR) in the treatment of inferior turbinate hypertrophy. METHODS A prospective randomized clinical trial study of 46 patients with bilateral inferior turbinate hypertrophy. Patients were randomly divided into 2 groups: PAT and SMR. RESULTS Intraoperative blood loss was ...