mannose-binding lectin (mbl) is a protein of innate immune system that is involved in opsonization and complement activation. mbl deficiency is associated with predisposition to infectious diseases; however subnormal levels are also seen in healthy subjects. the aim of this study was to investigate the prevalence and clinical manifestation of mbl deficiency in patients with increased susceptibi...

conclusions in conclusion, we developed a method to express the papg.acma protein on the surface of lactobacillus. this is the first report on the successful application of lactic acid bacteria displaying the papg.acma fusion protein. it will be interesting to determine the immune responses against the papg protein in near future using this surface display strategy. results the papg.acma fusion...

background: in this study, we examined the epidemiological aspects of neonatal mortality due to intrauterine infections with regard to regional characteristics. methods: consolidated report of the ministry of health and social development of the republic of kazakhstan on children deceased during their first 28 days of life due to intrauterine infections (p23 – congenital pneumonia, p35-39 – inf...

objective(s) staphylococcus aureus is a common cause of human infection, and emergence of vancomycin-resistance s. aureus  is a great concern for treatment of methicillin-resistant s. aureus,(mrsa) in recent years (mrsa). here, we report the isolation of high-level vrsa. materials and methods s. aureus was isolated from foot ulcer of a diabetic woman in tehran, iran. antibiotic susceptibility w...

background and aims: end-stage renal disease patients treated by hemodialysis (hd) are more susceptible for infection by viral hepatitis and human immunodeficiency virus (hiv) infections. infection by these viruses is promoted by the characteristic immunological dysfunction that develops in renal failure and interferes with the patient's ability to eliminate these viruses. prevalence of th...

background : people with sexually transmitted infections (stis) constitute the high-risk group for transmission of hiv. the present study was planned to estimate the prevalence of hiv and syphilis in patients attending sti clinic and to assess the socio-demographic determinants of the study subjects. methods : a cross sectional descriptive study of three-month duration was undertaken from janua...

conclusions our results showed that broad-spectrum antibiotics such as imipenem, meropenem, fosfomycin, cefoperazone/sulbactam, and vancomycin would be the first line and the most effective drugs for the empirical treatment of urinary tract pathogens due to their higher resistance rates against other drugs like cephalexin, cephradine, ciprofloxacin, levofloxacin, and norfloxacin. patients and m...

background: neutropenic patients are vulnerable to a wide spectrum of infectious agents. the aim of this study was to determine the current frequency of bacterial infections in patients with nosocomial fever and neutropenia. methods: in a retrospective study, the neutropenic patients’ specimens with nosocomial fever were cultured on blood and macconkey agar plates and evaluated at microbiology ...

patients and methods in this retrospective study, all urine samples of children hospitalized with urinary tract infection (288 patients, aged 1mon -14.5 years) during october 2008 to may 2011 were included in the study. after bacteria were identified by standard methods, antimicrobial susceptibility testing was performed using a panel of antimicrobial agents. results the most of patients were g...

conclusions the results of this study indicated that more than 90% of e. coli isolates harbored the fimh gene. the high binding ability of fimh could result in the increased pathogenicity of e. coli; thus, fimh could be used as a possible diagnostic marker and/or vaccine candidate. materials and methods a total of 140 isolated e. coli strains from patients with uti were identified using biochem...