objective(s): the major antibiotic efflux pump of esherichia coli is acrab-tolc. the first part of the pump, acrab, is encoded by acrab operon. the expression of this operon can be kept elevated by overexpression of an activator, mara following inactivation of marr and acrr repressors due to mutation in encoding genes, marr and acrr, respectively. the aims of this research were to use e. coli m...

conclusions despite the higher frequency of s. aureus nasal carriage in the interns, compared to the first year students, the difference did not reach statistical significance. therefore, attendance at medical centers cannot be considered a risk factor for increasing carriage. results out of the 200 nasal swabs obtained, the overall nasal carriage of s. aureus was 24.5% (49/200). the prevalence...

the occurrence of antibiotic-resistant pathogenic bacteria is becoming a serious problem. the rise of multiresistance strains has forced the pharmaceutical industry to come up with new generation of more effective and potent antibiotics, therefore creating development of antivirulence compounds. due to extensive usage of cell-to-cell bacterial communication (qs) systems to monitor the productio...

introduction urinary tract infection (uti) is one of the most common infections in childhood. appropriate treatment of uti requires to knowledge about antibiotic resistance patterns of common uropathogens. the aim of this study was to determine demographic, symptoms, signs and antibiotic resistance pattern in admitted infants with clinically diagnosis of uti in 17 shahrivar hospital of rasht ma...

background and objective: gastroenteritis is one of the most important diseases in the world. this disease is more critical among children, people with immune deficiency and the sufferers from mal-nutrition. shigella spp. as the most important cause of dysentery, causes much mortality around the world. increasing antibiotic resistance is one of the major health problems. this research aimed to ...

background and aims: acinetobacter baumannii is regarded as an important nosocomial pathogen around the world, especially in the intensive care unit that today seems to be resistant to the most antibiotics. therefore, this study aimed to trace classes 1, 2, and 3 integrin in the isolates resistant to acinetobacter baumannii. materials and methods: in this descriptive study, acinetobacter bauman...

conclusions the potential to form biofilm correlated with antibiotic resistance and ampc production in non-burn burn isolates of a. baumannii. on the other hand, the burn strains produced significantly higher amounts of esbl yet biofilm production was unrelated to antibiotic resistance or esbl-production. materials and methods sixty isolates of a. baumannii were employed of which, 30 were burn ...

conclusions only a few number of health workers do respect hygiene rules before and after catheterization. therefore, it is necessary to train health workers involved in such activities on good hygiene practices during catheterization. results two days later, (48 hours after the catheterization), 14 patients out of 60 (23.33%) presented with a urinary infection, of which 1 patient (1.66%) was a...

conclusions the current study results showed that silver nanoparticles produced by plantago ovata seed extract had an antibacterial effect on staphylococcus aureus which was resistant against cefixime, trimethoprim-sulfamethoxazole and penicillin. results the silver nanoparticles revealed gaussian distributions with the average diameter of 13 nm with some deviations, and results showed that the...

resistance to oxyimino cephalosporins antibiotics in enterobacteriaceae is primarily done by the extended spectrum β-lactamases (esbls). clear identification of risk factors for esbl-producing infections is necessary. therefore, efficient strategies can be developed to decrease outbreak of these infections. the aim of this study was to determine the antibacterial susceptibility and esbls patter...