BACKGROUND To summarize global research trends and activities on multimorbidity; then to assess the knowledge gaps and to identify implications for knowledge exchange between high income countries (HICs) and low- and middle- income countries (LMICs). METHODS A comprehensive search was conducted to identify research publications on multimorbidity in the Web of ScienceTM, as well as diabetes, d...

This paper presents a multidimensional approach to examining the urban evidence-policy interface in low- and middle-income countries (LMICs), and applies this approach to a case study from Pakistan. Key features of urban health policy and the significance of the evidence-policy interface in rapidly changing LMICs are articulated; characteristics of evidence that has been successfully incorporat...

This volume has shown that universal provision of a package of essential surgical services would avert an estimated 1.5 million deaths per year, or 6–7 percent of all avertable deaths in LMICs (Debas and others 2006; Mock and others 2015). Although approximately 234 million surgeries are performed worldwide each year, the distribution is very inequitable (Funk and others 2010). Nearly two billi...

Compelling evidence demonstrates links between greenspaces and human well-being. However, the existing has a strong bias towards high-income countries. Rapidly urbanising cities in low- middle-income countries (LMICs) remain largely unexplored. The rising prevalence of mental disorders LMICs highlights need to better understand role can play mitigating ill-health. We carried out cross-sectional...

BACKGROUND The 2004 Mexico Declaration, and subsequent World Health Assembly resolutions, proposed a concerted support for the global development of health policy and systems research (HPSR). This included coordination across partners and advocates for the field of HPSR to monitor the development of the field, while promoting decision-making power and implementing responsibilities in low- and m...

BACKGROUND Of the 1 billion people with hypertension globally, two-thirds reside in low- and middle-income countries (LMICs). The risk of hypertension in LMICs is thought to be positively associated with socioeconomic status (SES). However, recent studies have provided data inconsistent with this concept. Thus, we assessed the association between SES and hypertension in rural populations of LMI...

BACKGROUND The Surgical Safety Checklist (SSC) has been shown to reduce perioperative errors and complications and its implementation is recommended by the World Health Organisation (WHO). However, it is unknown how widely this intervention is used. We investigated attitudes and factors associated with use of WHO SSC in frontline medical professionals across the globe using a survey distributed...

Double burden of diseases in low– and middle–income countries (LMICs) is well recognised. However, proper understanding of the need for a joint intervention against both infectious diseases and non–communicable diseases (NCD) has arisen only recently [1]. In 2008, the proportion of premature deaths due to NCD in population under 60 years of age in low–income countries was 41%, in lower middle-i...

Worldwide trauma is currently the sixth leading cause of death, according to 10% of mortalities (1,2). Injury impact and the death from trauma are more common in males than females. People aged between 15 and 45 years include about half of the trauma deaths (3). Citizens of low- and middle-income countries (LMICs) account for 89% of all deaths from trauma worldwide. This is particularly because...

Kidney biopsies to elucidate the cause of chronic kidney disease (CKD) are performed in a minority of persons with CKD living in high-income countries, since associated conditions-that is, diabetes mellitus, vascular disease or obesity with pre-diabetes, prehypertension or dyslipidaemia-can inform management targeted at slowing CKD progression in a majority. However, attributes of CKD may diffe...