INTRODUCTION The necessity to develop new treatment options for challenging procedures in hernia surgery is becoming even more evident and tissue engineering and biological technologies offer even newer strategies to improve fascial healing. The present case reports a patient-tailored surgical technique performed to repair a grade IV abdominal incisional hernia, with a combined use of platelet-...

BACKGROUND Proteolytic degradation of extracellular matrix is a crucial step in the healing of incisional skin wounds. Thus, healing of skin wounds is delayed by either plasminogen-deficiency or by treatment with the broad-spectrum metalloproteinase (MP) inhibitor Galardin alone, while the two perturbations combined completely prevent wound healing. Both urokinase-type plasminogen activator and...

BACKGROUND Patients undergoing incisional/ventral hernia repair are at risk of developing several postoperative complications particularly venous thromboembolism (VTE), which is a major cause of morbidity and mortality. The aim of this study was to assess 30-day postoperative morbidity and mortality of patients undergoing incisional/ventral hernia repair and to determine the association between...

Wound healing responses of the tissues of the periodontium following periradicular surgery in rhesus monkeys were evaluated by light microscopy. Part II of this investigation reports the responses of mucoperiosteal and osseous tissues to blunt dissectional wounding resulting from the reflection of triangular or submarginal rectangular flaps. Healing of the dissectional wound is rapid, although ...

BACKGROUND AND AIM Cytokines are part of a family of molecules involved in the initiation, control and termination of the events that occurs in wound healing process. Aim of this study was to evaluate the production of some cytokines [interleukin (IL)-6, IL-10, IL-1alpha, IL-1ra, interferon (IFN)-gamma] in the drainage wound fluid from patients undergoing incisional hernia repair. METHODS Ten...

Platelet-derived growth factor (PDGF) is a potent activator for cells of mesenchymal origin. PDGF stimulates chemotaxis, proliferation, and new gene expression in monocytes-macrophages and fibroblasts in vitro, cell types considered essential for tissue repair. Therefore, we analyzed the influence of exogenously administered recombinant B chain homodimers of PDGF (PDGF-BB) on two experimental t...

BACKGROUND AND AIMS The clinical results of the vertical "vest-over-pants" Mayo repair were evaluated, and the risk factors for incisional hernia recurrence were studied. The purpose of this study is to point out the importance of reducing pre and post operative risk factors in the incisional hernia repair process in order to achieve a physiologically normal abdominal wall. METHODS Twenty pat...

The use of alloplastic-mesh is now a common practice in hernia repair around the world especially in the developed and industrialized countries [4].However in developing countries like Ghana, this methodology is either unknown by many local surgeons and general practitioners, or for fear of the unknown,it is not practiced. This study aimed to assess the appropriateness, outcomes and suitability...

OBJECTIVE To consider incisional endometrioma (IE) as a differential diagnosis of abdominal disorders and to recommend different treatments as preventive measures. Incisional endometrioma (IE), as a rare condition, usually develops in surgical scar of cesarean section or hysterectomy. MATERIALS AND METHODS We performed a retrospective review of 12 cases at Department of Surgery, Shahrekord Un...