Background Skin incision is considered to be placed at 90° in reference to the skin to get perfect wound edge adaptation. The incision on hair-bearing tissues, as the scalp, is considered to be bevelled at 45° to promote hair growth through the scar. There is no consensus about the preferred incision angle on the brow. The aim of this article was to demonstrate the feasibility of the "flat inci...

BACKGROUND Deep tissues and their afferents have unique responses to various stimuli and respond to injury distinctively. However, the types of receptors and endogenous ligands that have a key role in pain after deep tissue incision are unknown. TRPA1 has been shown to mediate pain-related responses in inflammation- and nerve injury-induced pain models. We hypothesized that TRPA1 has an importa...

years having had a pretty large number of abdominal emergencies, I have been able to put my opinion into practice. I will take the subject of acute appendicitis as an example of abdominal emergencies and because it is the commonest. Before discussing drainage I would like to write a few lines on the incision. Where the case has been diagnosed early and where pus is not present in a localised ab...

Treatment options for distal biceps tendon ruptures include nonoperative and operative approaches. Candidates for conservative nonoperative management include elderly low-demand patients, those in whom surgery is contraindicated because of medical comorbidities, and those who are unable to adhere to the strict postoperative rehabilitation regimen. Data have clearly shown the superiority of oper...

instrument with a small-diameter (less than 3 mm), a Mediflex disposable suture grasper closure device, as a percutaneous organholding device. The authors compared clinical outcomes between a single-port laparoscopic appendectomy (SPA) using a glove port with a percutaneous organ-holding device (group 1) and a SPA using a commercially-available multichannel single port (group 2). In group 1, a ...

Pogatzki, Esther M., G. F. Gebhart, and Timothy J. Brennan. Characterization of A and C-fibers innervating the plantar rat hindpaw one day after an incision. J Neurophysiol 87: 721–731, 2002; 10.1152/jn.00208.2001. Primary hyperalgesia after tissue injury is suggested to result from sensitization of primary afferent fibers, but sensitization to mechanical stimuli has been difficult to demonstra...

BACKGROUND Ptosis incidence following cataract surgery is reduced with a recently developed phacoemulsification technique using a small incision. However, it remains uncertain whether an upper transconjunctival sclerocorneal incision can cause minor blepharoptosis. In the present prospective study, patients underwent cataract surgery with either an upper or temporal 2.4-mm transconjunctival scl...

BACKGROUND Recent studies have implicated the activation of stress-activated mitogen-activated protein kinase (MAPK) p38 in spinal microglial cells for development of neuropathic and inflammatory pain. The aim of the present study was to investigate whether phosphorylation of p38 (p-p38) also mediates mechanical allodynia and thermal hyperalgesia induced by plantar incision. METHODS After rat...