the aim of this study was to develop an extended-release tablet formulation using a new in situ cross-linking method. the effects of polyvalent cations on theophylline release from tablets made with the polyanionic polymers sodium alginate and sodium carboxymethylcellulose, were investigated. different miliequivalents of the di and tri-valent cation, ca2+ and al3+, were added to tablet formulat...

abstract with increasing population, mine activities for metal proceeding are also increasing, so environment will be influenced by contaminant especially heavy metals. in situ immobilization of heavy metals using inexpensive amendments is considered as a simple and cost-effective approach for reducing heavy metal contamination. in this research we used sequential extraction for assessing reduc...

Abstract A method for small-scale testing and imaging of freestanding, microtomed polymer films using a push-to-pull device is presented. Central to this was the development sample preparation technique which utilized solvents at cryogenic temperatures transfer deposit delicate thin onto microfabricated devices. The focused ion beam (FIB)-milled tensile specimens enabled quantitative in situ TE...

background: flat urothelial lesions comprise a spectrum of morphologic changes ranging from reactive atypia to carcinoma in situ (cis). urothelial dysplasia and cis are associated with the recurrence and progression of urothelial carcinoma. distinguishing cis and dysplasia from reactive atypia based on histolopathogical features alone is often difficult. using different immunohistochemical mark...

knowledge of the orientation of horizontal in situ stresses is important to some areas of oil and gas field development plans. borehole breakouts observed in image logs and drilling-induced fractures are the main parameters for the determination of the stresses’ directions in situ. in this work, the orientations of borehole breakouts were investigated as a function of depth in oil wells a and b...

the present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. fourier transform infrared spectroscopy (ftir) and differential scannin...

purpose : to assess the outcomes of laser in situ keratomileusis (lasik) in patients with multiple sclerosis (ms) methods : 15 eyes of 8 patients with ms (2 men and 6 women) who referred for myopia treatment (with or without astigmatism) were undergone lasik. after refractive and visual acuity examinations, topographic and pachymetry screening, intraocular pressure (iop) measurement, biomicrosc...