Trimethylated lysine 27 on histone H3 (H3K27me3) is present in Drosophila, Arabidopsis, worms, and mammals, but is absent from yeasts that have been examined. We identified and analyzed H3K27me3 in the filamentous fungus Neurospora crassa and in other Neurospora species. H3K27me3 covers 6.8% of the N. crassa genome, encompassing 223 domains, including 774 genes, all of which are transcriptional...

An element $a$ in a ring $R$ is very clean in case there exists‎ ‎an idempotent $ein R$ such that $ae = ea$ and either $a‎- ‎e$ or $a‎ + ‎e$ is invertible‎. ‎An element $a$ in a ring $R$ is very $J$-clean‎ ‎provided that there exists an idempotent $ein R$ such that $ae =‎ ‎ea$ and either $a-ein J(R)$ or $a‎ + ‎ein J(R)$‎. ‎Let $R$ be a‎ ‎local ring‎, ‎and let $sin C(R)$‎. ‎We prove that $Ain K_...

The Aspergillus nidulans flbD gene encodes a protein with a Myb-like DNA-binding domain that is proposed to act in concert with other developmental regulators to control initiation of conidiophore development. We have identified a Neurospora crassa gene called rca-1 (regulator of conidiation in Aspergillus) based on its sequence similarity to flbD. We found that N. crassa rca-1 can complement t...

The role of shikimic acid as a common intermediate in the synthesis of phenylalanine, tyrosine, tryptophan, and p-aminobenzoic acid has been recognized for some time (l-3). The enzymes which catalyze the synthesis of shikimic acid from intermediates of carbohydrate metabolism have been observed in extracts of bacteria (4-6) as well as Neurospora crassa (7). On the other hand, the reactions lead...

Neurospora crassa has been utilized as a model organism for studying biological, regulatory, and circadian rhythms for over 50 years. These circadian cycles are driven at the molecular level by gene transcription events to prepare for environmental changes. N. crassa is typically found on woody biomass and is commonly studied on agar-containing medium which mimics its natural environment. We re...

Sequences coding for histone H3 and H4 of Neurospora crassa could be identified in genomic digests with the use of the corresponding genes from sea urchin and X. laevis as hybridization probes. A 2.6 kb HindIII-generated N. crassa DNA fragment, showing homology with the heterologous histone H3-gene probes was cloned in a charon 21A vector. Using DNA from this clone as a homologous hybridization...

P59Nc is a 59-kD polypeptide associated with 8-10-nm diameter cellular filaments in normal Neurospora crassa strains. Abnormally sized and shaped bundles of these structures are present in N. crassa strains carrying mutations at the locus sn (snowflake). By using molecular cloning and restriction fragment length polymorphism (RFLP) segregation analysis strategies we show here that sn is not the...

Objective: The aim of the present study was to examine the effectiveness of Acceptance and Commitment Therapy (ACT) combined with aerobic exercise (AE) on anxiety symptoms, insulin resistance (IR) and lipid profile in women with T2DMmellitus (T2DM). Materials and Methods: In the present study, 60 T2DM women with a mean age of 33.5 (± 3.52) years were selected from the patients who were referre...

Cercospora cf. sigesbeckiae is an ascomycete fungal pathogen that infects various plants, including important agricultural commodities, such as soybean. Here, we report the first draft genome sequence and assembly of this pathogen.