A target of best dissolution improvement of poorly soluble drugs is a necessity for the success of formulation in industry. The present work describes the preparation, optimization, and evaluation of a new spherical agglomeration technique for glimepiride as a model of poorly soluble drugs. It involved the emulsification of a drug solution containing a dispersed carrier that tailors the crystal...

Reading certainly has many purposes, one of which was by reading people can find out the information, increase knowledge and to expand horizons. Thus writer tried explore use mind mapping technique know significant improvement in students’ comprehension achievement recount text after being taught with mean difference students between who were using those not. The research design this study is...

purpose: customer satisfaction in modern organizations requires employees' job satisfaction that can be led to performance improvement in the organization. in this regard, self-leadership and strengthening of it among the employees and managers can facilitate this subject. the purpose of this paper is to study the relation between self-leadership with job satisfaction and performance impro...

This paper discusses a new principle of int.erronnection network for massively parallel arc,hit,ect,ures in t,he field of numerical comput,at,ion. The principle is motivated by an analysis of the applirat,ion feat,ures and the need to design new kind of rommunication networks combining very high hantlwidt,h, very low latency, performance independence t,o communication pattern or network load an...

17 moves, but if the move is uphill it is accepted by a certain probability, which decreases over time. The work by Swami and Gupta 18, 17] compares various heuristics and combinatorial algorithms. Their experiments suggest that iterative improvement is the best combinatorial optimization technique. Morzy, Matysiak, and Salza 11] improved the iterative improvement algorithm by maintaining a lis...

Statistical Inference of Function Through Evolutionary Relationships (SIFTER) is a powerful computational platform for probabilistic protein domain annotation. Nevertheless, SIFTER is not widely used, likely due to usability and scalability issues. Here we present SIFTER-T (SIFTER Throughput-optimized), a substantial improvement over SIFTER's original proof-of-principle implementation. SIFTER-T...

T-Cell Acute Lym-phoblastic Leukemia In article number 2205854, Jingjing Ye, Min Ji, Chunyan and co-workers observed aberrant adipogenesis in the bone marrow of chemotherapy-treated T-cell acute lymphoblastic leukemia (T-ALL) patients, differentiated-adipocytes attract support residual T-ALL cells. Last, an SREBF1 inhibitor demonstrates superior improvement on therapeutic effect dexamethason by...

The Joint Commission recently revised Information Management (IM) Standard IM.02.01.03, element of performance (EP) 5, Note 2, for laboratories. The revision is a result of a final rule effective April 7, 2014,* in which the US Department of Health & Human Services modified the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and the Health Insurance Portability and Accountability Act ...