In this work, an improved approach for computing cluster dissociation rates using Monte Carlo (MC) simulations is proposed and a discussion is provided on its applicability as a function of environmental variables (e.g., temperature). With an analytical transformation of the integrals required to compute variational transition state theory (vTST) dissociation rates, MC estimates of the expectat...

The potential of industrial wastewater reuse in Jordan is discussed. Industrial water requirements, wastewater production, types of pollutants in industrial wastewater and the technologies for wastewater treatment have been evaluated. A total of thirty industries have been reviewed. The total effluent from the thirty industries reviewed estimated at approximately 10,200 mVd. Of this amount, app...

Inhibition of Rho-associated coiled-coil kinase (ROCK) activity has been reported to promote recovery and growth of frozen-thawed human embryonic stem cells. Since in vitro-produced and/or manipulated bovine embryos are sensitive to cryopreservation, the present study was conducted to investigate whether the presence of ROCK inhibitor (Y-27632) in post-thaw culture medium improve the revivabili...

We examined whether a pretargeting method using a new recombinant anti-CD20 bispecific antibody (bsMAb) followed by (90)Y-1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid ((90)Y-DOTA)-peptide could reduce hematologic toxicity yet improve therapeutic responses compared with conventional (90)Y-anti-CD20 IgG and a chemically conjugated bsMAb. TF4, a humanized, tri-Fab bsMAb with two F...

UNLABELLED We determined whether therapeutic responses using a bispecific antibody that pretargeted (90)Y-hapten-peptide radioimmunotherapy or a directly radiolabeled, humanized, (90)Y-anti-CD20 IgG (veltuzumab) could be improved by combining these treatments with unlabeled humanized antibodies against CD22 (epratuzumab), CD74 (milatuzumab), or veltuzumab. METHODS Nude mice bearing establishe...

Given a high dimensional p-vector of continuous predictors X and a univariate response Y , principal fitted components (PFC) provide a sufficient reduction of X that retains all regression information about Y in X while reducing the dimensionality. The reduction is a set of linear combinations of all the p predictors, where with the use of a flexible set of basis functions, predictors related t...