نتایج جستجو برای: imp3 protein

تعداد نتایج: 1234739  

2015
Yoshihiro Yoshitake Daiki Fukuma Akira Yuno Masatoshi Hirayama Masashi Nagata Yasuo Kenta Kawahara Yoshihiro Nakagawa Ryoji Yoshida Akiyuki Hirosue Hidenao Ogi Akimitsu Hiraki Hirofumi Jono Akinobu Hamada Koji Yoshida Yasuharu Nishimura Masanori Shinohara

Purpose: The peptides derived from ideal cancer–testis antigens, including LY6K, CDCA1, and IMP3 (identified using genome-wide cDNA microarray analyses), were used in immunotherapy for head and neck squamous cell cancer (HNSCC). In this trial, we analyzed the immune response to and safety and efficacy of vaccine therapy. Experimental Design: A total of 37 patients with advanced HNSCCwere enroll...

2010
Jeanette E Eckel-Passow Christine M Lohse Yuri Sheinin Paul L Crispen Christopher J Krco Eugene D Kwon

BACKGROUND Although tissue microarrays (TMAs) are commonly employed in clinical and basic-science research, there are no guidelines for evaluating the appropriateness of a TMA for a given biomarker and tumor type. Furthermore, TMA performance across multiple biomarkers has not been systematically explored. METHODS A simulated TMA with between 1 and 10 cores was designed to study tumor express...

Journal: :ESMO open 2022

Breast cancer is the most common worldwide. Tumor metastasis cause of death in breast cancer. In view high mortality patients, there a need to identify new prognostic biomarkers. IMP3 has role induction Epithelial-Mesenchymal Transition (EMT) and SLUG an EMT marker. Both these have been implicated metastasis. Hence, might prove be potential therapeutic targets future. This was retrospective stu...

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