Image registration is an important and fundamental task in image processing used to match two different images. Given two or more different images to be registered, image registration estimates the parameters of the geometrical transformation model that maps the sensed images back to its reference image. A feature-based approach to automated imageto-image registration is presented. The characte...

G. K. Rohde, S. Pajevic, C. Pierpaoli, P. J. Basser National Institutes of Health, Bethesda, Maryland, United States SYNOPSIS: With the advent of new MR imaging modalities such as DT-MRI, MRA, and CSI, demand for image registration procedures capable of dealing with multi-channel image data has increased. A novel method based on multivariate linear correlation is proposed to align two multi-cha...

INTRODUCTION: He MRI is increasingly useful for regionally evaluating ventilation in mouse models of asthma before and after challenge with Methacholine (MCh) [1,2] Such changes can be effectively quantified by suitably normalizing the preand post-MCh images, and subtracting the two to generate a difference map depicting regional changes in ventilation[3]. However, difference mapping can in som...

on achieving my goal. His observations and comments helped me to establish the overall direction of the research and to move forward with investigation in depth. I would also like to thank my parents who gave me the opportunity to study. Without their support, I would have never got this far. Finally, I would like to dedicate this thesis to my wife, Yi-Chun, for her love, patience, and understa...

In this paper we discuss image registration techniques with a focus on volume preserving constraints. These constraints can reduce the non-uniqueness of the registration problem significantly. Our implementation is based on a constrained optimization formulation. To solve the problem we use a variant of the Sequential Quadratic Programming method. Moreover, we present results on synthetic as we...