نتایج جستجو برای: il1b

تعداد نتایج: 724  

2017
Yanting Shen Lu Bu Rui Li Zhenzhu Chen Fei Tian Na Lu Qinyu Ge Yunfei Bai Zuhong Lu

Tumor metastasis is a multistep process involving a number of genetic alterations so that the genetic diagnosis is got increasingly attentions today. The aim of this study was to use RNA-seq to screen the effective differential expression genes in the peripheral blood mononuclear cells for the hepatic carcinoma with metastasis. The results showed that hepatic carcinoma samples gathered accordin...

2015
Chi-Keung Wan Peng Li Rosanne Spolski Jangsuk Oh Allison B. Andraski Ning Du Zu-Xi Yu Christopher P. Dillon Douglas R. Green Warren J. Leonard

The canonical pathway for IL-1β production requires TLR-mediated NF-κB-dependent Il1b gene induction, followed by caspase-containing inflammasome-mediated processing of pro-IL-1β. Here we show that IL-21 unexpectedly induces IL-1β production in conventional dendritic cells (cDCs) via a STAT3-dependent but NF-κB-independent pathway. IL-21 does not induce Il1b expression in CD4(+) T cells, with d...

Journal: :Blood 2000
J Tsukada Y Toda M Misago Y Tanaka P E Auron S Eto

The activation status of a recently identified STAT (signal transducers and activators of transcription) factor, LIL-Stat (lipopolysaccharide [LPS]/IL-1-inducible Stat) in adult T-cell leukemia (ATL) cells was investigated by electrophoretic mobility shift assays using nuclear extracts of leukemic cells from 7 patients with ATL and a GAS (gamma interferon activation site)-like element termed LI...

Journal: :Cytogenetics and cell genetics 1999
N L Lòpez-Corrales T S Sonstegard T P Smith

The PAX8 gene, a member of the human paired box gene family, was mapped by FISH to chromosome 11 in cattle and goat and to the short arm of chromosome 3 in sheep. The cytogenetic position of PAX8 on BTA 11 and on its homologue OAR 3p lies in the region where the interleukin beta (IL1B) gene has been previously located, (BTA 11q22. 1-->q22.3 and OAR 3p25-->q26 respectively; Lòpez-Corrales et al....

Journal: :Proceedings of the National Academy of Sciences 2018

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