The aim of our study is to assess the local cytokine levels as prognostic factors for early relapse in NMIBC patients. 75 patients with were enrolled study: 51 primary and 24 initially recurrent NMIBC, LG HG tumors diagnosed each group. Patients monitored during 9 months after treatment: TURB chemotherapy (No. 6). During samples taken, supernatants obtained tissue measured (IL-1β, IL-6, IL-10, ...