OBJECTIVES The aim of the study was to determine the prevalence of nausea in pediatric patients with pain-associated functional gastrointestinal disorders (FGIDs), examine the effect on social and school functioning, and examine the applicability of pediatric Rome III criteria. METHODS A total of 221 pediatric patients (6-18 years of age) with chronic abdominal pain prospectively completed a ...

M. Rebuzzi, F. Fasano, V. Vinicola, G. Hagberg, M. Di Mario, B. Maraviglia, and S. Capuani Physics, Sapienza University of Rome, Rome, Rome, Italy, CNR-INFM SOFT, Rome, Rome, Italy, IRCCS Santa Lucia Foundation, Rome, Rome, Italy, Rehabilitation Hospital, IRCCS Santa Lucia Foundation, Rome, Rome, Italy, Neuroimaging laboratory, IRCCS Santa Lucia Foundation, Rome, Rome, Italy, Radiology, IRCCS S...

OBJECTIVES The aim was to document, from the perspective of the empirical literature, the primary symptoms of functional dyspepsia (FD), evaluate the extent to which existing questionnaires target those symptoms, and, finally, identify any missing evidence that would impact the questionnaires' use in regulated clinical trials to assess treatment efficacy claims intended for product labeling. ...

BACKGROUND Since mortality in congenital diaphragmatic hernia (CDH) is decreasing, morbidity such as neurodevelopmental outcome is becoming increasingly important. OBJECTIVES We evaluated neurodevelopmental outcome in high-risk CDH patients treated according to the CDH EURO Consortium standardized treatment protocol. METHODS This observational, prospective cohort study was conducted in two ...

PURPOSE Overactive bladder (OAB) is a manifestation of urgency, regardless of urge incontinence, due to involuntary bladder contraction during the storage period. There is a close association between constipation and OAB, but constipation cannot be readily diagnosed. The aims of this study were to evaluate the prevalence of constipation in OAB and the consequent therapeutic effects according to...

BACKGROUND Dyspepsia is a common problem in the community and clinical practice with symptom(s) considered arising from the gastroduodenal region. Dyspepsia burden and associated factors vary from country to country. The aim of this study was to determine the prevalence of uninvestigated dyspepsia (UD) using Rome III criteria, associated risk factors and self-reported dyspepsia symptoms' correl...