Although benign prostatic hyperplasia (BPH) is often viewed as an inevitable concomitant of the aging process, recent research establishes that this syndrome is significantly more common in men with metabolic syndrome. Moreover, twentienth century epidemiology focusing on quasi-vegan rural China reveals that this syndrome may in fact be substantially preventable. The decline in cellular apoptos...

Insulin-like growth factor (1GFJ.s circulate in plasma as large mol wt proteins bound to specific proteins, termed IGF-binding proteins (IGFBPs). As IGFBPs have been shown to produce artifacts in IGF radioligand assays, various extraction procedures have been proposed to eliminate IGFBPs from biological samples before radioligand assays. Comparison of acid-ethanol and C,, Sep-Pak extraction met...

Insulin-like growth factor I (IGF-I) is a potent inducer of oligodendrocyte development and myelination in perinatal stages of development. The growth hormone (GH), the main regulator of IGF-I levels in postnatal life, has also been suggested to have a role in myelination during development, although this is still controversial. We report a stimulatory effect of both GH and IGF-I on olygodendro...