The coexistence of immune (idiopathic) thrombocytopenic purpura (ITP) and Crohn’s disease (CD) is rare. We performed a review of cases of concomitant ITP and CD in the English and Japanese literature. Among 17 identified cases of concomitant ITP and CD, ITP was initially diagnosed in four cases and CD was initially diagnosed first in six cases. Simultaneous diagnoses were reported in the remain...

Abbreviations: acute myeloid leukemia, (AML); American Society of Clinical Oncology, (ASCO); bone marrow, (BM); end stage renal disease, (ESRD); erythropoietin, (EPO); granulocyte colony-stimulating factor, (G-CSF); Granulocyte-macrophage colony-stimulating factor, (GM-CSF); hematopoietic growth factors, (HGFs); hematopoietic stem cell, (HSC); hemoglobin, (Hgb); idiopathic thrombocytopenic purp...

Med J Malaysia Vol 67 No 3 June 2012 INTRODUCTION Autoimmune hepatitis (AIH), which predominantly affects women and usually responds to immunosuppressive therapy, is a disease characterized by hypergammaglobulinemia, increased titers of serum tissue autoantibody, and an immunogenetic background. This disease can present with a variety of coexisting non-hepatic disorders presumably caused by imm...

BACKGROUND Idiopathic thrombocytopenic purpura (ITP) is a hematological disorder and can be classified as acute or chronic. The main goal of treatment for acute childhood ITP is the prevention of potentially fatal bleeding complications, the most serious of which is intracranial hemorrhage (ICH). Treatment options for acute childhood ITP include splenectomy, corticosteroids, and blood products ...

conclusions: in this study, a higher rate of more severe itp in recently vaccinated young children was observed in comparison with other probable etiologies. further investigations are needed to explain this finding. results: 51 patients were enrolled in this study (mean age = 3.86 ± 1.53 months; males = 32 [62.7%]). in 33 (64.7%) patients the platelets level was below 20000 /mm3. thrombocytope...

background: the autoimmune disease known as idiopathic (immune thrombocytopenic purpura thrombocytopenic purpura (itp) is clinically defined by a low numbers of platelets in the circulation blood. this study aimed to isolate autoantibodies made against the platelet glycoproteins using platelets from healthy volunteers, to determine their specificity and further elucidate their effects on platel...

Idiopathic Thrombocytopenic Purpura (ITP) is an autoimmune disorder. ITP can occur in children and adults. This disease be fatal because the platelet count low due to destruction of excessive platelets so that it interfere with vital organs bleeding occurs. The lack knowledge ordinary people about disease, many assume bruises nosebleeds on body are caused by fatigue. For that, we need a system ...

Eleven patients with adult idiopathic thrombocytopenic purpura (ITP) were treated with bolus methylprednisolone at doses of 1 g/day for 3 days. In nine of eleven patients the platelet count rose to more than 100 X 10(9)/l during 2-9 days. In two other patients, it rose to 81 X 10(9)/l and 43 X 10(9)/l. In six of eleven patients splenectomy was carried out without any platelet transfusion when t...

Described herein, a case of Langerhans cell histiocytosis (LCH) in an adult with Idiopathic Thrombocytopenic Purpura (ITP) diagnosed at age ten. She presented with cranial diabetes insipidus, later developed hypogonadotrophic hypogonadism and multiple cervical lympadenopathy from which histopathology of excisional biopsy confirmed LCH. Magnetic resonance imaging showed thickened pituitary stalk...