A 46-year-old female presented to the emergency room due to the chief complaint of left-sided weakness. By imaging study, she was diagnosed with cerebral infarction. Thrombolytic and antiplatelet agents were not considered due to the "golden hour" for treatment having passed and a low platelet count. The peripheral blood smear, bone marrow biopsy, and aspirate findings were consistent with immu...

Idiopathic Thrombocytopenic Purpura (ITP) is a hematological disease characterized by decreased number of blood platelets. Clinically, children with ITP may present petechiae, ecchymoses, haematuria, epistaxis and occasionally hemorrhage. Oral manifestations include spontaneous gingival bleeding, petechiae or hematomas of the mucosa, palate and tongue. It is important for dentists to be aware o...

Posterior reversible encephalopathy syndrome (PRES) was first identified in 1996, and is typically caused by acute hypertension, renal decompensation, fluid retention, and treatment with immunosuppressants. Predisposing conditions include hypertension, eclampsia, autoimmune disease, leukemia, non-Hodgkin lymphoma (NHL), Idiopathic Thrombocytopenic Purpura (ITP), and Thrombotic Thrombocytopenic ...

Thrombotic thrombocytopenic purpura is a disseminated form of thrombotic microangiopathy. Although most cases are assumed to be idiopathic, its association with malignancy is well-recognized and it usually occurs at the terminal stage of cancer. The condition is characterized by microangiopathic hemolytic anemia and thrombocytopenia. It is generally idiopathic, and its association with adenocar...

T HE OPPORTUNITY presented itself recently for the study of a case of chronic idiopathic thrombocytopenic purpura characterized by the presence of unusually large agranular platelets. Several features indicated that the platelets were physiologically defective and led to the diagnosis of a thrombopathic or thrombasthenic type of thrombocytopenic purpura. When a blood transfusion from a polycyth...

The measurement of platelet-associated IgG (PAIgG) is a potentially useful diagnostic test for idiopathic thrombocytopenia purpura (ITP). However, the restricted application of PAIgG measurements to thrombocytopenic populations primarily comprised of ITP patients will artificially enhance its diagnosis specificity. For this reason, we performed a prospective study in which the results of a sens...