purpose : to examine the safety and efficacy of simultaneous ahmed glaucoma valve (agv) implantation with intravitreal and intracameral injection of bevacizumab (ivb and icb) in patients with refractory acute neovascular glaucoma (nvg) with very high intraocular pressure (iop) and active neovascularization of the iris (nvi) and/or the angle (nva) methods : in a prospective interventional study,...

European Journal of ImmunologyVolume 51, Issue 3 Back CoverFree Access cover story: Eur. J. Immunol. 3'21 First published: 03 March 2021 https://doi.org/10.1002/eji.202170038AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions Use check box below share version article.I have rea...

A better understanding of tumor infiltrating leukocyte (TIL) differentiation is necessary to advance therapeutic strategies and inform melanoma patient outcomes. We have previously identified that the transcriptome CD8+ TILs can be placed on a spectrum early activation late memory states. Halting in associated with poor response immune checkpoint blockade (ICB), whereas progression towards resi...

Abstract The heat extracted from the core by overlying mantle across core‐mantle boundary controls thermal evolution of core. This in turn leads to solidification inner association with exsolution light alloying elements into liquid outer Although temperature (T) at (ICB) would be adjusted account for effects elements, melting T Fe places an upper bound ICB and it is a vital point profile Here,...

Sana Khalid1, Sobia Idrees1, Hina Khalid1, Bilal Hussain1, Sandeep Tiwari2, Syed Shah Hassan2, Artur Silva3, Vasco Azevedo2 and Syed Babar Jamal2* 1Department of Bioinformatics and Biotechnology, Government College University Faisalabad, Pakistan 2Departamento de Biologia Geral, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais, Brazil 3Instituto de Ciências Biológica...

The protection and current flow regulation of high-voltage direct-current (HVDC) grids requires the deployment additional semiconductor-based equipment including dc circuit breakers (DCCBs) controllers (CFCs). However, inclusion multiple devices could significantly increase total cost an HVDC system. To potentially reduce costs, this paper presents innovative multi-function integrated DCCB (MF-...

&&v,w To assess the penetration of Iossrtan and L-158,338 into the rabbit eye after topical application and their effects on the IOP of ocular hypertensive cynomolgus monkeys. M&Q& Penetration was indirectly assessed in albino rabbits using an & assay. Aliquots of aqueous humor were sampled one hour after the bilateral topical instillation of one drop (50 uL) of 2% solutions of losartsn or L-15...

Purpose: To examine the safety and efficacy of simultaneous Ahmed glaucoma valve (AGV) implantation with intravitreal and intracameral injection of bevacizumab (IVB and ICB) in patients with refractory acute neovascular glaucoma (NVG) with very high intraocular pressure (IOP) and active neovascularization of the iris (NVI) and/or the angle (NVA) Methods: In a prospective interventional study, p...

Abstract Mucosal associated invariant T (MAIT) cells are innate like T-cells that recognise non-peptide metabolite antigens presented on monomorphic MHC related-1 (MR1) making them an attractive off the shelf tool for cancer immunotherapy. In this study, we investigate function of MAITs in tumor microenvironment neoadjuvant anti-PD1 treated lung patients (NCT02259621). Paired single cell RNA/TC...

The appropriate treatment of ventilator-associated pneumonia (VAP) must be based on accurate diagnosis, which can be done by microbiological examination of the samples obtained from the respiratory tract by nonbronchoscopic bronchoalveolar lavages (NB-BAL). This study was designed to determine the effectiveness of NB-BAL in diagnosing VAP in newborns. Two hundred and seven NB-BAL samples were o...