نتایج جستجو برای: iacrimal sac

تعداد نتایج: 14381  

2013
Nawreen Rahman Jochen Buck Lonny R. Levin

Soluble adenylyl cyclase (sAC) is a source of the second messenger cyclic adenosine 3', 5' monophosphate (cAMP). sAC is directly regulated by bicarbonate (HCO(-) 3) ions. In living cells, HCO(-) 3 ions are in nearly instantaneous equilibrium with carbon dioxide (CO2) and pH due to the ubiquitous presence of carbonic anhydrases. Numerous biological processes are regulated by CO2, HCO(-) 3, and/o...

2014
Ahmed Rattani P.K. Vinod Jonathan Godwin Kikuë Tachibana-Konwalski Magda Wolna Marcos Malumbres Béla Novák Kim Nasmyth

Activation of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) by Cdc20 is delayed by the spindle assembly checkpoint (SAC). When all kinetochores come under tension, the SAC is turned off and APC/C(Cdc20) degrades cyclin B and securin, which activates separase [1]. The latter then cleaves cohesin holding sister chromatids together [2]. Because cohesin cleavage also destroys the tension resp...

Journal: :Biochemical and biophysical research communications 2015
Takenori Miyashita James L Burford Young-Kwon Hong Haykanush Gevorgyan Lisa Lam Hiroshi Hoshikawa Nozomu Mori Janos Peti-Peterdi

This study describes a technical breakthrough in endolymphatic sac research, made possible by the use of the recently generated Prox1-GFP transgenic mouse model. Whole-mount imaging techniques through the decalcified temporal bone and three-dimensional observations of Prox1-GFP mouse tissue revealed the positive labeling of the endolymphatic sac in adult stage, and allowed, for the first time, ...

2017
Hidetaka Kumagami Mariko Terakado Yuzuru Saino Akiko Baba Daisuke Fujiyama Tomomi Fukuda Kenji Takasaki Haruo Takahashi

The immunohistochemical expression pattern and the physiological role of transient receptor potential vanilloid (TRPV) 4 in the endolymphatic sac were investigated. TRPV4 was expressed predominantly in the apical membrane of the mitochondria-rich cells and cell volume regulation by TRPV4 was observed in a tissue culture of the rat endolymphatic sac. TRPV4 was also present in the endolymphatic s...

Journal: :Critique d’art 2016

Journal: :Pathobiology : journal of immunopathology, molecular and cellular biology 2012
Yosuke Shida Takahiro Fujimori Hiroyuki Tanaka Yukari Fujimori Ryusuke Kimura Hirofumi Ueda Kazuhito Ichikawa Shigeki Tomita Hitoshi Nagata Keiichi Kubota Masahiro Tsubaki Hiroyuki Kato Takashi Yao Tamotsu Sugai Kenichi Sugihara Yasuo Ohkura Johji Imura

OBJECTIVE Serrated adenocarcinoma (SAC), proposed as a new pathologic type, arises predominantly in the right side of the colon and has a poorer prognosis than conventional colorectal carcinoma. The prognosis of colorectal carcinoma is variable in Dukes' B, so the aim of this study was to determine whether or not SAC has a poor prognosis in Dukes' B. METHODS The study group comprised 64 patie...

2012
Pablo Lara-Gonzalez Stephen S. Taylor

The Spindle Assembly Checkpoint (SAC) delays the onset of anaphase in response to unattached kinetochores by inhibiting the activity of the Anaphase-Promoting Complex/Cyclosome (APC/C), an E3 ubiquitin ligase. Once all the chromosomes have bioriented, SAC signalling is somehow silenced, which allows progression through mitosis. Recent studies suggest that the APC/C itself participates in SAC si...

Journal: :International Journal of Pharmaceutics 2021

In this study, the molecular state of ritonavir (RTN)-saccharin (SAC) coamorphous incorporated into mesoporous silica by solvent evaporation and effect SAC on RTN dissolution from mesopores were investigated. The amorphization RTN-SAC was confirmed as a halo pattern in powder X-ray diffraction measurements single glass transition event modulated differential scanning calorimetry (MDSC) curve. 1...

Journal: :IEEE Potentials 2022

Greetings, everyone! It’s an honor to be appointed as the vice chair for membership of 2022 Member and Geographic Activities–Student Activities Committee (SAC) IEEE. I look forward opportunity serve more than 120,000 IEEE Student Members worldwide through SAC programs. We have some exciting plans this year. If you any creative ideas would like implement them with SAC, please send us email at sa...

2017

1. A mucocele of the lacrimal sac, or 2. Chronic dacryocystitis or conjunctivitis due to lacrimal sac obstruction, or 3. Congenital nasolacrimal duct obstruction that cannot be cured by probing (members should be over 1 year of age), or 4. Epiphora (excessive tearing) due to acquired obstruction within the nasolacrimal sac and duct, or 5. Lacrimal sac infection that must be relieved before intr...

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