Although serotonin 5-HT1A receptors couple to several Gi/o Gprotein subtypes, little is known concerning their differential activation patterns. In this study, in membranes of Chinese hamster ovary cells expressing h5-hydroxytryptamine1A receptors (CHOh5-HT1A), isotherms of 5-HT-stimulated guanosine-5 -O-(3[S]thio)-triphosphate ([S]GTP S) binding were biphasic, suggesting coupling to multiple G...

Introduction: Fig. 1a shows a first-order log-domain filter [1] which is ideally linear and time-invariant (LTI) [1, 2] between the large signal currents i1p and i4p in its input and output transistors (Fig. 1a, assuming i1p > 0). i1p is the sum of an AC input signal iin and a bias Ibias. In traditional implementations, Ibias is a constant. The output ioutp is obtained by subtracting (I2/I3)Ibi...

where detξ denotes the determinant of ξ, and (C4) W (PξQ) = W (ξ) for all ξ ∈ M and all P,Q ∈ SO(3) for N = 3, with SO(3) := {Q ∈ M : QQ = QQ = I3 and detQ = 1}, where I3 denotes the identity matrix in M 3×3 and Q is the transposed matrix of Q. (In fact, (C4) is an additional condition which is not related to (2). However, it means that W is frame-indifferent, i.e., W (Pξ) = W (ξ) for all ξ ∈ M...

Three case histories of patients with isolated traumatic tricuspid regurgitation are reported. Clinical features are compared and contrasted to the I3 cases previously reported. The benign nature of the lesion is emphasized by the long-term follow-up periods of 39, I3, and 31 years respectively. The presence of a normal systolic pressure in the right ventricle may be one reason why isolated sev...

The Host Identity Indirection Infrastructure (Hi3) is a networking architecture for mobile hosts, derived from the Internet Indirection Infrastructure (i3) and the Host Identity Protocol (HIP). Hi3 has efficient support for secure mobility and multihoming, which both are crucial for future Internet applications. In this paper, we describe and analyze Hi3 in detail. Compared to existing solution...

This paper reports on an action research project involving a structured, formative assessment feedback process, within a personal learning environment (PLE), to address concerns about effectiveness of previous course delivery. The project ran during session 2006-07 involving the use of a series of tutor mediated self and peer assessed core tasks associated with five distinct learning milestones...

where detξ denotes the determinant of ξ, and (C4) W (PξQ) = W (ξ) for all ξ ∈ M and all P,Q ∈ SO(3) for N = 3, with SO(3) := {Q ∈ M : QQ = QQ = I3 and detQ = 1}, where I3 denotes the identity matrix in M 3×3 and Q is the transposed matrix of Q. (In fact, (C4) is an additional condition which is not related to (2). However, it means that W is frame-indifferent, i.e., W (Pξ) = W (ξ) for all ξ ∈ M...