SIR, It has been suggested that HTLV-I infection may be associated with the development of some connective tissue diseases (CTD), including polyand dermatomyositis (PM and DM), systemic lupus erythematosus (SLE), scleroderma, and Sjogrens syndrome (SS).' 2 This was based on eight case reports in which neither the ethnic origin of their patients nor the assays used to determine HTLV-I seropositi...

SIR, It has been suggested that HTLV-I infection may be associated with the development of some connective tissue diseases (CTD), including polyand dermatomyositis (PM and DM), systemic lupus erythematosus (SLE), scleroderma, and Sjogrens syndrome (SS).' 2 This was based on eight case reports in which neither the ethnic origin of their patients nor the assays used to determine HTLV-I seropositi...

SIR, It has been suggested that HTLV-I infection may be associated with the development of some connective tissue diseases (CTD), including polyand dermatomyositis (PM and DM), systemic lupus erythematosus (SLE), scleroderma, and Sjogrens syndrome (SS).' 2 This was based on eight case reports in which neither the ethnic origin of their patients nor the assays used to determine HTLV-I seropositi...

K?r?m-Kongo kanamal? ate?i (KKKA) Bunyaviridae familyas?ndan kene kaynakl? bir virüsün neden oldu?u potansiyel olarak ölümcül zoonoz hastal?kt?r. KKKA virüsü, virüs ta??yan kenelerinin ?s?rmas?yla, hastalar?n ve enfekte hayvanlar?n kan? veya dokular? ile temas yoluyla insanlara bula??r. ?nsan enfeksiyonlar? spesifik olmayan ate?li semptomlarla ba?lar, ancak vaka fatalitesiolan ciddi hemorajik s...

To determine whether a newly developed enzyme-linked immunosorbent assay (ELISA), which detects antibodies directed against glycoprotein I (gI) of pseudorabies virus, is suitable for serodiagnosis, it was compared with a conventional ELISA and two neutralization tests. The gI ELISA was 99.2% as sensitive and 100% as specific as the conventional ELISA. Antibody titers measured by the gI ELISA we...

Filariasis is a major burden in India in states like Andhra Pradesh. With launching of global filariasis elimination program it has become necessary to use sensitive and accurate methods for diagnosis of filariae as compared to conventional methods. We in this study tried to compare the results of detection of microfilariae with conventional slide methods compared with the ELISA method. 90 samp...

Expression of HTLV-I p19 protein in an Escherichia coli expression system always leads to the formation of inclusion body. Solubilisation and refolding of the inclusion bodies is complex, time consuming and difficult during large-scale preparation. This study aimed to express and purify a soluble form of recombinant HTLV-I p19 protein in an E. coli expression system. The synthetic DNA encoding ...

A yolk protein enzyme-linked immunosorbent assay (YP-ELISA) was developed for the predator Orius insidiosus (Say). The YP-ELISA is intended to assess reproductive response to dietary and other rearing conditions, and to assist in quality control and diet development for mass rearing. Hybridomas and monoclonal antibodies were produced against homogenates of eggs dissected from females. Hybridoma...