OBJECTIVE To determine the prevalence of molar incisor hypomineralization (MIH) and any associated causes of MIH in children from two rural divisions in Kenya. DESIGN Prospective cross-sectional study. SETTING Seventeen primary schools in Matungulu and Kangundo divisions of Machakos district in Kenya. SUBJECTS All six to eight year-olds in the seventeen primary schools. RESULTS A total ...

Hypophosphatasia is a metabolic bone disease characterized by bone and teeth hypomineralization due to defective function of tissue-nonspecific alkaline phosphatase (TNSALP). The disorder is caused by various mutations in the TNSALP gene localized on short arm of chromosome 1. Infantile hypophosphatasia is a severe form of the disease inherited as an autosomal recessive trait which presents bef...

Sickle cell anemia is an inherited defect that affects the structure and synthesis of hemoglobin. In sickle cell trait, the affected individuals carry one gene for the abnormal hemoglobin (HbS). Sickle cell disease, however, is the homozygous state in which the abnormal hemoglobin is predominant in red blood cells, leading to devastating multisystem problems. Complications of the disease in chi...

Anomalies in amelogenesis may be due to developmental defects or abnormalities in different components of developing teeth and can affect dental development. We compared dental development in a group of children with molar-incisor hypomineralization (MIH) with that in age- and sex-matched controls. Dental age was determined using panoramic radiographs of 105 children (59 girls, 46 boys) aged 7-...

Congenital contractural arachnodactyly (CCA) is an inherited disorder of connective tissue similar to Marfan's syndrome. The craniofacial and oral features of a young girl with CCA are described. The patient has the typical features of CCA as well as some additional dental anomalies which have not previously been reported with this syndrome. These include banded pitted enamel hypoplasia and hyp...

Objective: This work aims to determine prevalence and consequences of Molar Incisor Hypomineralization in the city Ouro Verde – SP. Methodology: 457 children, students from municipal school EMEF Julia Roseira Jerônimo were examined, aging 7 11 years old. Clinical examinations for diagnosis performed by a single trained calibrated examiner using criteria proposed European Academy Pediatric Denti...