Peroxisome proliferator activated receptors (PPARs) are a family of related receptors implicated in a diverse array of biological processes. There are 3 main isotypes of PPARs known as PPARalpha, PPARbeta and PPARgamma and each is organized into domains associated with a function such as ligand binding, activation and DNA binding. PPARs are activated by ligands, which can be both endogenous suc...

BACKGROUND & OBJECTIVE A group of villages in Kollam district of Kerala, southern part of India are exposed to a higher dose of natural radiation than global average. Yet no adverse health effects have been found in humans, animals and plants in these areas. The present study was carried out to understand whether radiation affects the quantity and quality of flavonoids in plants grown in this a...

of several large clinical trials, with cardiovascular disease (CVD) end-points, in the general population [2]. In the above-mentioned post hoc analyses, apart from the increased risk for type I errors [2], there are several limitations. Renal failure patients were excluded [1] and results regarding CKD progression are often based on fewer patients than initially included in the study [3]; glome...

Introduction:This study was carried out to investigate the effect of bael(Aegle marmelos) on glucose,cholesterol,triglyceride,creatinine levels and the activity of ALT and AST in the serum of diabetic rats.   Method:45 Adult male sprague dawley rats were selected.the brats were divided into three groups.the first group was considered as negative CONTROL(non-diabetic rats)and diabetes mellitus...