BACKGROUND Biological theories on respiratory regulation have linked separation anxiety disorder (SAD) to panic disorder (PD). We tested if SAD children show similarly increased anxious and psychophysiological responding to voluntary hyperventilation and compromised recovery thereafter as has been observed in PD patients. METHODS Participants were 49 children (5-14 years old) with SAD, 21 cli...

The Hyperventilation Test is widely used in the "bed-side examination" of vestibular patients. It can either activate a latent nystagmus in central or peripheral vestibular diseases or it can interact with a spontaneous nystagmus, by reducing it or increasing it. Aims of this study were to determine the incidence, patterns and temporal characteristics of Hyperventilation-induced nystagmus in pa...

MOST PHYSICIANS are quite familiar with the isolated attack of acute hyperventilation that is characterized by dramatic overbreathingand classically culminates in tetany. Although terrifying to the patient, and almost equally alarming to any onlooker, these attacks are usually brief and without serious medical sequelae. Recently we have come to recognize a chronic hyperventilation pattern that ...

OBJECTIVE To observe the effect of voluntary hyperventilation on electroencephalographic activity during routine EEG recording on patients referred to a tertiary care hospital. METHODS This was an observational study conducted at Neurophysiology Lab, Department of Neurology at Liaquat National Hospital, Karachi from May 2007 to September 2007. Data of 326 patients was collected prospectively ...

INTRODUCTION The concentration of 2,3-diphosphoglycerate (2,3-DPG/Hct) increases as a physiological occurrence to pH increase and hyperventilation. This response was tested in patients with severe traumatic brain injury (TBI). METHOD The concentration of 2,3-DPG/Hct was measured daily for six days in eleven patients with severe TBI in need of optimized hyperventilation because of intracranial...

Hyperventilation with mixtures of O2 and CO2 has long been known to enhance carbon monoxide (CO) elimination at low HbCO levels in animals and humans. The effect of this therapy on oxygen delivery (DO2) has not been studied. Isocapnic hyperventilation utilizing mechanical ventilation may decrease cardiac output and therefore decrease DO2 while increasing CO elimination. We studied the effects o...