Introduction: The examination of the placenta gives a clear idea what happened with fetus when it was in mother’s womb. changes women pregnancy induced hypertension and normal pregnancies can be compared. Objective: This study done to find out differences gross structure histology between hypertensive placentas. Methods: Placenta from case control group collected Gynecology Obstetrics Departmen...

With the use of ambulatory monitoring, a circadian blood pressure pattern has been shown to characterize normotensive as well as hypertensive pregnant women. However, the potential differences between healthy and complicated pregnancies in pulse pressure, an independent marker of cardiovascular risk in the general population, have not yet been investigated. We analyzed 2523 blood pressure serie...

Background: Hypertensive disorders and intrauterine growth restriction are common complications encountered during pregnancy. This study was conducted to observe the usefulness of systolic/ diastolic (S/D) ratio in umbilical artery as compared with non-stress test (NST) predict perinatal outcome pregnancies complicated hypertensive (IUGR). Methods: It a prospective observational which on patien...

Hypertension disorders complicate up to 10%-11% of all pregnancies and remain leading causes of poor outcome, including placental abruption, organ failure, cerebrovascular accident and disseminated intravascular coagulation. These disorders are also associated with increased risk of perinatal death, fetal intrauterine growth restriction, and prematurity/preterm delivery. Epidemiological evidenc...

OBJECTIVE To assess the role of Doppler uterine artery screening in the prediction of recurring hypertensive disorders in a high-risk population. METHODS Ninety-four women with a history of hypertensive disorders in previous pregnancies underwent ultrasound color Doppler to analyze blood flow in the uterine arteries at 21-22 weeks of gestation. We evaluated the performance of the Pulsatility ...

Preeclampsia(PE) is a hypertensive disorder affecting about 5-14% of pregnancies worldwide and around 20% high-risk pregnancies, resulting in maternal perinatal morbidity mortality. Imbalances milieu serum sodium potassium, that are involved functioning vascular smooth muscles, leads to vasoconstriction hypertension PE. Calcium deficiency stimulates parathyroid hormone, leading vasoconstriction...

The aim of this study was to evaluate quantitative aberrations of novel fetal-specific epigenetic markers in maternal plasma of pregnancies with hypertensive disorders. We compared the concentrations of DSCR3, RASSF1A, and SRY as cell-free fetal DNA markers in 188 normal pregnancies, 16 pregnancies with early-onset preeclampsia (EO-PE), 47 pregnancies with late-onset preeclampsia (LO-PE), and 2...

BACKGROUND Preeclampsia and gestational hypertensive disorders are thought to occur due to endothelial cell dysfunction and abnormal placentation, triggered by angiogenesis-related factors yet undetermined. The aim of this study was to investigate whether a genetic polymorphism (SNP) of Histidine-rich glycoprotein (HRG), HRG C633T SNP, is associated with gestational hypertensive disorders. ME...