Extracts of Hypericum perforatum L. (St John’s wort) are now successfully Abstract competing for status as a standard antidepressant therapy. Because of this, great effort has been devoted to identifying the active antidepressant compounds in the extract. From a phytochemical point of view, St John’s wort is one of the best-investigated medicinal plants. A series of bioactive compounds has been...

Despite the widespread raw material base of St. John's wort in nature, there is an urgent need to cultivate it [4,5]. In this regard, already some experience growing crops and developed basic elements cultivation technology.

Hypericum perforatum, commonly known as St. John’s Wort, has been found to exhibit many medicinal, especially anti-depressant, properties. Hypericin is thought to be the main chemical constituent responsible for H. perforatum’s medicinal properties. We report here the ability of H. perforatum and hypericin to inhibit the growth of mouse mammary cancer CRL2539 cells. H. perforatum, at concentrat...

AIM To evaluate the effects of montelukast and Hypericum perforatum against ischemia/reperfusion (I/R)-induced intestinal damage. MATERIALS AND METHODS Twenty-eight hamsters were divided into 4 groups following midline abdominal laparotomy: control group (n = 7), I/R group (n = 7), montelukast and I/R (MIR) group (n = 7), and Hypericum perforatum and I/R (HPIR) group (n = 7). After 60 min of ...

A standardised 50% aqueous ethanolic extract of the Indian variety of Hypericum perforatum (IHp) was examined for its putative anti-inflammatory and analgesic activity at the doses of 100 and 200 mg/kg, po. The experimental paradigms used were carrageenan induced pedal edema and cotton pellet induced granuloma for anti-inflammatory activity, whereas the tail flick, hot plate and acetic acid ind...