We analyzed O2 pulse, the total volume of O2 consumed per heart beat, in guinea pigs at pressures from 10 to 60 atmospheres. Animals were placed in a hyperbaric chamber and breathed 2% O2 in either helium (heliox) or hydrogen (hydrox). Oxygen consumption rate (VO2) was measured by gas chromatographic analysis. Core temperature and heart rate were measured by using surgically implanted radiotele...

Weaver LK, Howe S, Snow GL, Deru K. Arterial and pulmonary arterial hemodynamics and oxygen delivery/extraction in normal humans exposed to hyperbaric air and oxygen. J Appl Physiol 107: 336–345, 2009. First published April 30, 2009; doi:10.1152/japplphysiol.91012.2008.— Divers and hyperbaric chamber attendants breathe hyperbaric air routinely. Hyperbaric oxygen (HBO2) is used therapeutically f...

Objective(s): The aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression.  In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac tissue following exposure to hyperbaric pressure. Materials and Methods:Expression of CD11b and CD...

Hyperbaric oxygen therapy (HBOT) is an adjuvant novel non-invasive treatment technique in the field of plastic surgery for treating different wounds. This utilizes 100% at pressures above atmospheric pressure. In our study, we are discussing about eight cases surgery. HBOT plays important role pathological conditions. It involves a hundred percent breathing closed chamber certain period time. m...

Weaver LK, Hopkins RO, Chan KJ, et al. Hyperbaric oxygen for acute carbon monoxide poisoning. QUESTION: In patients with carbon monoxide poisoning, is hyperbaric oxygen (HBO) more effective than normobaric oxygen for reducing cognitive sequelae? Design Randomised (allocation concealed*), blinded (patients, outcome assessors, and statisticians),* controlled trial with follow up at 6 weeks, 6 mon...

Hyperbaric oxygen (HBO) treatment was shown to be beneficial as an additional treatment for ischemic muscles in crush injuries and ischemia-reperfusion injuries. The purpose of this study was to assess the influence of hyperbaric oxygen treatment on transcriptional myogenic factors during muscle regeneration. Those factors (MyoD, myf5, myogenin, mrf4) are essential for determination and differe...

OBJECTIVE To catalog the side effects of 2.4 atmospheres absolute (atm abs) hyperbaric oxygen (HBO2) vs. sham on post-concussion symptoms in military service members with combat-related, mild traumatic brain injury (TBI). METHODS Fifty subjects diagnosed with TBI were randomized to either a sham (1.3 atm abs breathing air) or treatment (2.4 atm abs breathing 100% oxygen) hyperbaric profile. F...