Free hydroxyproline inhibits the formation of protein-bound hydroxyproline from proline to a considerably greater extent than it does the incorporation of proline into protein of auxin-treated Avena coleoptiles. This inhibition is greater in the wall than in the cytoplasmic fraction. In the absence of auxin, free hydroxyproline exerts little or no inhibition of hydroxyproline formation. Further...

Since nearly all of the hydroxyproline of the body is found in collagen, it has been suggested (1, 2) that the urinary excretion of this imino acid may be an important index of collagen metabolism. The origin of urinary hydroxyproline, however, is not definitely established. The isotopic studies of Stetten (3) in rats indirectly suggested that most of the free and peptide hydroxyproline in the ...

Background: Tilapia farming is amongst the most lucrative in terms of yield and return investments aquaculture industry Thailand. The sustainable supply tilapia (Oreochromis spp.) can be exploited to reconsider fish species as a huge potential for Thailand’s medical sector, particularly on xenograft an innovative treatment burns. Methods: Collagen content quantification by high-performance liqu...

Pyridine 2,4-dicarboxylic acid is a structural analog of 2-oxoglutarate and is known to inhibit 2-oxoglutare-dependent dioxygenases. The effect of this inhibitor in tomato seedlings grown in MS media supplied with various concentrations of PDCA was investigated, resulting in shorter roots and hypocotyls in a dose-dependent manner. The partial inhibition of growth in roots was more drastic compa...

Fibrosis is the final common pathway for various tissue lesions that lead to chronic progressive organ failure, and consequently effective antifibrotic drugs are strongly desired. However, there are few animal models in which it is possible to evaluate fibrosis sensitively in a short period of time. We therefore generated two transgenic rats harboring a firefly luciferase reporter gene under th...

morinda citrifolia (noni) has been traditionally used for bone and wound healing.   the present study was carried out to investigate the effect of morinda citrifolia leaves on experimental wounds and lipid peroxide levels in rats. effect of aqueous extract of leaves of morinda citrifolia (200 mg/kg) on excision, resutured incision and dead space wound models were studied. measurement of blood m...

The significance of urinary hydroxyproline has not been completely clarified. It appears, however, that this amino acid excretion is correlated with either synthesis or destruction of collagen. Collagen hydroxyproline is reported to be formed by the irreversible hydroxylation of peptid-linked proline and no free hydroxyproline is incorporated directly into this protein. Therefore, the changes o...

Background: Osteoporosis is one of the prevalent diseases post-Menopausal women. Hence to evaluate severity osteoporosis serum calcium, ALP and urinary hydroxyproline used as bone resorption marker.Method: 30 post-menopausal women with were compared healthy pre-menopausal 25-40 years Random Blood sample collected from venipuncture centrifuged get serum. Fasting Urine was 1.2 drops 6 N HCI added...

The effect of VAM on reducing wilt caused by Fusarium oxysporum Schlecht. f.sp. fragariae Winks et Williams (FO) infection in strawberry and the possible mechanisms involved were investigated. Two key substance involved in disease defenses, lignin and hydroxyproline-rich glycoprotein were induced and formed in the cell wall of strawberry root, and the peak content of lignin and hydroxyproline-r...