Article history: Received 17 July 2015 Revised 18 December 2015 Accepted in revised form 19 December 2015 Available online 21 December 2015 The main challenges of biological implants are suitable strength, adhesion, biocompatibility and corrosion resistance. This paper discusses fabrication, characterization and electrochemical investigation of anodized Ti6Al4V without and with a hydroxyapatite...

Promoting and understanding the formation of hydroxyapatite on biocompatible metals in the body is a very important topic of biomaterials research. In this paper, the formation of hydroxyapatite on a near-β Ti-13Nb-13Zr alloy by immersion in minimal essential medium (MEM) with and without the addition of H2O2 has been studied using electrochemical methods, SEM and XPS. The Ti-13Nb-13Zr alloy ex...

Strategies for bone tissue engineering and regeneration rely on bioactive scaffolds to mimic the natural extracellular matrix and act as templates onto which cells attach, multiply, migrate and function. Of particular interest are nanocomposites and organic-inorganic (O/I) hybrid biomaterials based on selective combinations of biodegradable polymers and bioactive inorganic materials. In this pa...

Colloidal apatitic nanosphere of 2-5 nm in diameter was synthesized in the presence of poly(acrylic acid), PAA. PAA, which has long been recognized as an inhibitor in the synthesis of hydroxyapatite, is used as a structure-directing agent for the synthesis of calcium-deficient apatite (CDHA) in this study. Experimental observation suggests a critical amount of the low-molecular-weight PAA, abov...

Nanocomposites have emerged in the last two decades as an efficient strategy to upgrade the structural and functional properties of synthetic polymers. Aliphatic polyesters as polylactide (PLA), poly(glycolides) (PGA), poly(3-caprolactone) (PCL) have attracted wide attention for their biodegradability and biocompatibility in the human body. A logic consequence has been the introduction of organ...

A common feature of the outer layer of protective biological exoskeletons is structural anisotropy. Here, we directly quantify the mechanical anisotropy and fracture of an individual material layer of a hydroxyapatite-based nanocomposite exoskeleton, the outmost ganoine of Polypterus senegalus scale. Uniaxial compression was conducted on cylindrical micropillars of ganoine fabricated via focuse...

Introduction: The need for biocompatible and bioactive scaffolds to accelerate the regeneration and repair of fractured bones has been considered for bone tissue engineering applications during recent decades. The new methods were developed to produce scaffolds to improve the tissue quality, size of cavities, control the porosity and increase the scaffold compressive strength u...