Reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2- carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)- substituted-quinolines (lo), which were converted to compound 11 with phosphorus oxychloride. Substituted-2-(l-methyl-5-nitro-2-imidazo1yl)-4.- methyl-(or phenyl-) quinolines (14) were prepared through the reaction of 2- acetyl-5-nitro-1-methy...

The reactions of [(thf)2TiCl4] with sodiated 2,2’-bis[2-hydroxy-3,5-di(tert-butyl)benzylideneamino]-1,1’-biphenyl (1 a) and 2,2’-bis[2-hydroxy-3,5-di(tert-butyl)benzylideneamino]-4,4’-dimethyl-1,1’-biphenyl b) yield the corresponding Ti complexes 2 a b. Similarly, 1 reacts [(thf)2ZrCl4] to Zr derivative 3. For a, mixture cis-β trans isomers were observed in solution whereas congener exclusively...

Abstract A series of isoflavone functionalized 3,4‐dihydro‐1,3‐oxazine hybrids was synthesized in good to excellent yields through a Mannich‐type condensation cyclization reaction 6‐chloro‐7‐hydroxy‐3‐(2‐methoxy‐phenyl)‐chromen‐4‐one or 6‐chloro‐7‐hydroxy‐3‐(2‐methoxy‐phenyl)‐chromene‐4‐thione with formaldehyde and primary amines. After spectroscopic characterization, these newly prepared were ...

Many benzo[b]furan lignans are known to be biologically active in nature. 2-(3'-Methoxy-4'-hydroxy-phenyl)-5-(3-hydroxypropyl)-7-methoxy-benzo[b]furan-3-carbaldehyde (XH-14) is found as a bioactive component isolated from the plant Salvia miltiorrhiza, commonly known as Danshen, which is a traditional Chinese medicine that is used as a cardiovascular medication. This study examined whether 3 di...

MnL,CuL,CoL,NiL,CrL,FeL and ZnL (L = [2,4,6-trihydroxy phenyl ] Imidazo[4,5] 1,10phenanthroline),MnL 2 ,CuL 2 ,CoL 2 ,NiL 2 ,CrL 2 ,FeL 2 and ZnL 2 (L 2 = (5-Bromo,3-Methoxy Phenyl) Imidazo [4,5] 1,10Phenanthroline), MnL,CuL,CoL,NiL,CrL,FeL and ZnL (L=2,4,6-trifluro phenyl Imidazo [4,5] 1,10-phenanthroline), MnL,CuL,CoL,NiL,CrL,FeL and ZnL (L=4-ethyl phenyl Imidazo[4,5] 1,10-phenanthroline), Mn...

A new molecule of 2-[3, 4 di hydroxy phenyl] 3, 5, 14-trihydroxy 13oxo 2H-chromeno [34:5, 6] pyrano [2, 3-h] 4H-chromene 4-one was synthesized and screened. This new compound was synthesized by incorporating 4-chloro-3-formyl coumarin group with quercetin compound. In the present study the antioxidant and antimalarial activities of new 2-[3, 4 di hydroxy phenyl] 3, 5, 14-trihydroxy 13oxo 2H-chr...

3-Hydroxy-β-ionone, a flavor and fragrance compound with fruity violet-like characteristics, is widely applied in foodstuff beverages, currently produced using synthetic chemistry. In this study, novel lutein cleavage enzyme (EhLCD) was purified characterized from Enterobacter hormaechei YT-3 to convert 3-hydroxy-β-ionone. Enzyme EhLCD homogeneity by ammonium sulfate precipitation, Q-Sepharose,...

Background Cancer is the second most common cause of death. Oral squamous cell carcinoma (OSCC) represents frequent all oral neoplasms. Many treatment modalities such as chemotherapy, radiotherapy, surgery, and immunotherapy are emerging but still, patients' quality life questionable. Despite advances in therapeutic approaches, percentages morbidity mortality OSCC have not improved significantl...

( )-Cryptocaryalactone (6-[2-acetoxY-4-phenyl-3-butenyl}5,6-dihydro-2-pyranone) and ()-deacetylcryptocaryalactone (6-[2-hydroxy-4-phenyl-3-butenyIJ-5,6-dihydro-2-pyranone) isolated from Cryptocarya moschata seeds are natural germination inhibitors. Applied at 0.004 M, the second compound completely arrested germination of velvetleaf (Abulilolllheophrasli) and decreased the germination rate of s...