A plasma- and precursor-assisted biomimetic process utilizing plasma and alternate dipping treatments was applied to a Leed-Keio artificial ligament to produce a thin coating of apatite in a supersaturated calcium phosphate solution. Following plasma surface modification, the specimen was alternately dipped in calcium and phosphate ion solutions three times (alternate dipping treatment) to crea...

During the last few years Strontium has been shown to have beneficial effects when incorporated at certain doses in bone by stimulating bone formation. It is believed that its presence locally at the interface between an implant and bone will enhance osteointegration and therefore, ensure the longevity of a joint prosthesis. In this study we explore the possibility of incorporating Sr into nano...

Highly porous poly(L-lactic acid)/apatite composites were prepared through in situ formation of carbonated apatite onto poly(L-lactic acid) foams in a simulated body fluid. The highly porous polymer foams (up to 95% porosity) were prepared from polymer solution by solid-liquid phase separation and subsequent sublimation of the solvent. The foams were then immersed in the simulated body fluid at...

Biological apatite is an inorganic calcium phosphate salt in apatite form and nano size with a biological derivation. It is also the main inorganic component of biological hard tissues such as bones and teeth of vertebrates. Consequently, biological apatite has a wide application in dentistry and orthopedics by using as dental fillers and bone substitutes for bone reconstruction and regeneratio...

The experimental results were quantitatively compared with the theory based on a physical model representing the reaction and with the experiments involving synthetic hydroxyapatite discs. The experimental initial rates self-consistently compared well with the theoretical predictions. An analysis of the experimental initial rate data yielded a reaction constant, ti. for the reaction representin...

The feasibility of natural apatite for adsorptive removal of Fe from aqueous solution was investigated. Batch experiments were performed as function of process parameters such as contact time, initial concentration of Fe, temperature, apatite dosage and pH. The natural apatite exhibited a high performance for the removal of Fe from aqueous solution. The pH value clearly affects the removal mech...

Nanocrystals of apatitic calcium phosphate impart the organic-inorganic nanocomposite in bone with favorable mechanical properties. So far, the factors preventing crystal growth beyond the favorable thickness of ca. 3 nm have not been identified. Here we show that the apatite surfaces are studded with strongly bound citrate molecules, whose signals have been identified unambiguously by multinuc...

To render polymeric materials osteoinductive, nano-sized calcium phosphate apatite particles (CaP) were introduced into a low molecular weight poly(D,L-lactide). Homogenous composites were made with 10%, 20% and 40% by weight of apatite content while pure polylactide was used as control. Thereafter porous samples (pore size 300-400 microm, 60% porosity) were fabricated and sterilized. In vitro ...

Introduction: The calcium phosphate ceramics, in particular hydroxyapatite ( HA), has shown to be capable of conducting bone formation and forming a chemical bond to bone. Because of this osteoconductivity, HA ceramic has been applied in joint reconstruction in the form of coating on joint implants such as hip stems by plasma spraying technique. Direct bone apposition has been repeatedly demons...